David Danielle
Laboratoire de Biologie Animale-Université de Clermont, France.
Wilhelm Roux Arch Entwickl Mech Org. 1972 Mar;170(1):1-12. doi: 10.1007/BF00575519.
Experimental associations of gastric epithelium of the Rabbit foetus with homologous or heterologous mesenchyme, separated by membrane filter or "partially" associated, permit us to prove the existence of two types of inductors.The first factor induces the epithelial morphogenesis. It is thermostable and highly diffusible.The second factor, organospecific, is more or less favorable to the differentiation of the gastric epithelium according to the nature of the mesenchyme. Lightly diffusible and thermolabile, it is elaborated in the cytoplasmic phase of the mesenchymal cells.
将兔胎儿的胃上皮与同源或异源间充质通过膜滤器分离或“部分”联合进行实验关联,使我们能够证明存在两种诱导物。第一种因素诱导上皮形态发生。它耐热且高度可扩散。第二种因素具有器官特异性,根据间充质的性质,对胃上皮的分化或多或少有利。它扩散性较弱且不耐热,在间充质细胞的细胞质阶段形成。