Ursprung Heinrich, Sofer William H, Burroughs Natalie
Department of Biology, The Johns Hopkins University, Baltimore, Maryland.
Laboratory for Developmental Biology, ETH, Sonneggstrasse 5, Zürich, Switzerland.
Wilhelm Roux Arch Entwickl Mech Org. 1970 Sep;164(3):201-208. doi: 10.1007/BF00582032.
Alcohol dehydrogenase (ADH) activity inDrosophila larvae and adults is localized primarily in fat body, intestine, and Malpighian tubules. In adult males, it occurs furthermore in derivatives of the genital disk.When expressed as ADH activity/whole organism, increasing values are found throughout the larval stages. Around the time of puparium formation, the activity decreases, to increase again around hatching of the adult.As the genital disk undergoes metamorphosis, it synthesizes (or activates) ADH rather than acquiring the enzyme from elsewhere in the organism.
果蝇幼虫和成虫体内的乙醇脱氢酶（ADH）活性主要定位于脂肪体、肠道和马氏管。在成年雄性果蝇中，该酶还存在于生殖盘衍生物中。以ADH活性/整个生物体来表示时，在幼虫各个阶段可发现其值不断增加。在化蛹形成前后，该活性下降，而在成虫孵化前后又再次上升。随着生殖盘经历变态发育，它合成（或激活）ADH，而非从生物体其他部位获取该酶。
