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糖尿病患者胎儿脑功能的4D评估

4D assessment of fetal brain function in diabetic patients.

作者信息

Antsaklis Panagiotis, Porovic Selma, Daskalakis George, Kurjak Asim

机构信息

.

出版信息

J Perinat Med. 2017 Aug 28;45(6):711-715. doi: 10.1515/jpm-2016-0394.

DOI:10.1515/jpm-2016-0394
PMID:28306540
Abstract

OBJECTIVE

To assess whether there is a difference in the behavior of fetuses of pregnant women with diabetes under treatment with insulin, compared to fetuses of pregnant women without diabetes.

MATERIALS AND METHODS

Kurjak's antenatal neurodevelopmental test (KANET) - a method that, by application of four-dimensional (4D) ultrasound, assesses fetal behavior in a similar way that neonatologists perform a neurological assessment in newborns - was applied from 28 to 38 weeks of gestation to 40 pregnancies with pre-existing diabetes mellitus or gestational diabetes mellitus (GDM) requiring insulin (diabetic group) and to 40 non-diabetic cases, with otherwise low-risk pregnancies (non-diabetic group).

RESULTS

There were no statistically significant differences regarding maternal age (30.5±5.1 years for diabetic group vs. 29.8±6.2 years for non-diabetic group) and gestational age (32±1.6 weeks for the diabetic group compared to 33±1.2 weeks for the non-diabetic group). After analysis of the results obtained from application of KANET to each group, results of KANET had higher scores in the non-diabetic group.

CONCLUSION

It appears that there are differences in the fetal behavior between diabetic and non-diabetic fetuses, and also the specific parameters - movements that were different between the two groups were identified.

摘要

目的

评估接受胰岛素治疗的糖尿病孕妇的胎儿行为与非糖尿病孕妇的胎儿行为是否存在差异。

材料与方法

库尔亚克产前神经发育测试(KANET)——一种通过应用四维(4D)超声,以类似于新生儿科医生对新生儿进行神经评估的方式来评估胎儿行为的方法——在妊娠28至38周期间应用于40例患有孕前糖尿病或妊娠期糖尿病(GDM)且需要胰岛素治疗的孕妇(糖尿病组)以及40例低风险非糖尿病孕妇(非糖尿病组)。

结果

两组孕妇在年龄(糖尿病组为30.5±5.1岁,非糖尿病组为29.8±6.2岁)和孕周(糖尿病组为32±1.6周,非糖尿病组为33±1.2周)方面无统计学显著差异。在对每组应用KANET所获得的结果进行分析后,KANET的结果在非糖尿病组得分更高。

结论

糖尿病胎儿与非糖尿病胎儿的行为似乎存在差异,并且还确定了两组之间不同的特定参数——运动情况。

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4D assessment of fetal brain function in diabetic patients.糖尿病患者胎儿脑功能的4D评估
J Perinat Med. 2017 Aug 28;45(6):711-715. doi: 10.1515/jpm-2016-0394.
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The fetal cerebro-placental ratio in diabetic pregnancies is influenced more by the umbilical artery rather than middle cerebral artery pulsatility index.糖尿病妊娠中的胎儿脑-胎盘比值受脐动脉的影响大于大脑中动脉搏动指数。
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