Tomov T, Ankov V
Vutr Boles. 1987;26(6):81-8.
The study includes 115 men, 17 to 26 years of age, suffering from various forms of male hypogonadism: Klinefelter's syndrome--40 patients, male Turner's syndrome--2 patients, primary hypogonadism with other etiology--14 patients, cryptorchism--12 patients, anorchidism--8 patients, secondary hypogonadism--26 patients and late puberty--13 patients. A raised hydrocortisone plasma level was found. In the anorchidism cases the basic testosterone level was the lowest one combined with the highest basic hydrocortisone level. The 24 hour rhythm of hydrocortisone secretion in Klinefelter's syndrome is regular but the hour values are higher. In cases of primary hypogonadism with other etiology, cryptorchism and secondary hypogonadism the 24 hour rhythm is disturbed and the hydrocortisone values are higher.
该研究纳入了115名年龄在17至26岁之间、患有各种形式男性性腺功能减退的男性：克兰费尔特综合征——40例患者，男性特纳综合征——2例患者，其他病因引起的原发性性腺功能减退——14例患者，隐睾症——12例患者，无睾症——8例患者，继发性性腺功能减退——26例患者，青春期延迟——13例患者。发现血浆氢化可的松水平升高。在无睾症病例中，基础睾酮水平最低，同时基础氢化可的松水平最高。克兰费尔特综合征中氢化可的松分泌的24小时节律是正常的，但各小时值较高。在其他病因引起的原发性性腺功能减退、隐睾症和继发性性腺功能减退病例中，24小时节律紊乱，氢化可的松值较高。
