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[黄鼠(Citellus parryi)冬眠期间红细胞膜脂质非特异性修饰的作用]

[Role of the nonspecific modification of erythrocyte membrane lipids during hibernation in the suslik Citellus parryi].

作者信息

Lapinskiĭ A G, Nevretdinova Z G

出版信息

Zh Evol Biokhim Fiziol. 1987 Nov-Dec;23(6):711-6.

PMID:2830751
Abstract

Studies have been made on the content of cholesterol, phospholipids, fatty acid composition, the intensity of lipid peroxidation, the activity of Na+, K+-ATPase, as well as on the peroxide hemolysis in the erythrocytes in prehibernating and hibernating ground squirrels. Changes in partial content of cholesterol and in fatty acid composition of membranes are presumably due to the excessive lipid peroxidation during hibernation resulting from the decrease in the activity of antioxidative enzymes, which also accounts for the increase in peroxide hemolysis of erythrocytes.

摘要

已经对冬眠前和冬眠期间的地松鼠红细胞中的胆固醇含量、磷脂、脂肪酸组成、脂质过氧化强度、Na+,K+-ATP酶活性以及过氧化物溶血进行了研究。膜中胆固醇部分含量的变化和脂肪酸组成的变化可能是由于冬眠期间抗氧化酶活性降低导致脂质过氧化过度,这也解释了红细胞过氧化物溶血的增加。

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