de Chaffoy de Courcelles D, Leysen J E, de Clerck F
Department of Biochemistry, Janssen Pharmaceutica Research Laboratories, Beerse, Belgium.
Experientia. 1988 Feb 15;44(2):131-3. doi: 10.1007/BF01952195.
The signal transducing system coupled to the serotonin-S2 receptor on platelets involves metabolism of inositol-containing phospholipid, elevation of intracellular free Ca2+ and activation of protein kinase C. Evidence for coupling of the serotonin-S2 receptor to the same signal transducing system in brain and smooth muscle tissue is reviewed.
