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T2的鉴定;肝脏微粒体葡萄糖-6-磷酸酶系统的磷酸盐/焦磷酸盐转运蛋白。

The identification of T2; the phosphate/pyrophosphate transport protein of the hepatic microsomal glucose-6-phosphatase system.

作者信息

Waddell I D, Lindsay J G, Burchell A

机构信息

Department of Medicine, Ninewells Hospital and Medical School, University of Dundee, Scotland.

出版信息

FEBS Lett. 1988 Feb 29;229(1):179-82. doi: 10.1016/0014-5793(88)80822-6.

DOI:10.1016/0014-5793(88)80822-6
PMID:2831086
Abstract

The phosphate/pyrophosphate translocase protein (T2) of the hepatic microsomal glucose-6-phosphatase system was identified and then purified using antibodies raised against the rat mitochondrial phosphate/hydroxyl ion antiport protein. The T2 protein was shown to be absent in the microsomes isolated from a patient previously diagnosed as having type lc glycogen storage disease.

摘要

肝微粒体葡萄糖-6-磷酸酶系统的磷酸/焦磷酸转运蛋白(T2)被鉴定出来,然后使用针对大鼠线粒体磷酸/氢氧根离子反向转运蛋白产生的抗体进行纯化。结果显示,从一名先前被诊断为患有lc型糖原贮积病的患者分离出的微粒体中不存在T2蛋白。

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The identification of T2; the phosphate/pyrophosphate transport protein of the hepatic microsomal glucose-6-phosphatase system.T2的鉴定;肝脏微粒体葡萄糖-6-磷酸酶系统的磷酸盐/焦磷酸盐转运蛋白。
FEBS Lett. 1988 Feb 29;229(1):179-82. doi: 10.1016/0014-5793(88)80822-6.
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