Neel Gregory S, Nagel Thomas H, Hoxworth Joseph M, Lal Devyani
Department of Otolaryngology-Head & Neck Surgery, Mayo Clinic, 5777 East Mayo Bouelvard, Phoenix, AZ 85054, USA.
Section of Neuroradiology, Department of Radiology, Mayo Clinic, 5777 East Mayo Bouelvard, Phoenix, AZ 85054, USA.
Otolaryngol Clin North Am. 2017 Apr;50(2):347-364. doi: 10.1016/j.otc.2016.12.010.
The orbit may be frequently involved by sinonasal or ventral skull base malignancy. This involvement bodes a poorer prognosis for survival. Multimodality therapy with surgery and radiation therapy is usually attempted to optimize local control and overall survival. Oncologic surgical resection with negative margins is critical to local control and survival. In the past, any involvement of the orbit was deemed to necessitate orbital sacrifice. However, contemporary studies show that in carefully selected cases, orbital preservation does not adversely impact survival. In addition, novel reconstructive techniques can help minimize complications and optimize functional and aesthetic outcomes.
鼻窦或颅底腹侧恶性肿瘤常累及眼眶。这种累及预示着较差的生存预后。通常尝试采用手术和放射治疗的多模式疗法来优化局部控制和总体生存率。切缘阴性的肿瘤外科切除对于局部控制和生存至关重要。过去，眼眶的任何累及都被认为需要牺牲眼眶。然而，当代研究表明，在精心挑选的病例中，保留眼眶不会对生存产生不利影响。此外，新的重建技术有助于将并发症降至最低，并优化功能和美学效果。
