Abdou Rami, Baredes Soly
Department of Otolaryngology - Head and Neck Surgery, Neurological Institute of New Jersey, Rutgers New Jersey Medical School, 90 Bergen Street, Suite 8100, Newark, NJ 07103, USA.
Department of Otolaryngology - Head and Neck Surgery, Neurological Institute of New Jersey, Rutgers New Jersey Medical School, 90 Bergen Street, Suite 8100, Newark, NJ 07103, USA.
Otolaryngol Clin North Am. 2017 Apr;50(2):481-497. doi: 10.1016/j.otc.2016.12.019.
Population-based cancer registries allow for data collection on the scale of large populations, outside the limits of a single institution, and facilitate study of rare entities. The SEER database has been used to study more than 7000 cases encompassing a wide variety of relatively rare sinonasal malignant histologies. Clinically useful parameters have been gleaned from these analyses. Important limitations, such as omission of chemotherapy data, surgical approach used, type of radiation administered, and selection and confounding bias, should be considered. Nevertheless, population-based analyses yield readily generalizable and clinically relevant information regarding the management of sinonasal malignancies for the practicing clinician.
基于人群的癌症登记系统能够在单一机构范围之外对大量人群的数据进行收集，并便于对罕见病例进行研究。监测、流行病学与最终结果（SEER）数据库已被用于研究7000多例涵盖各种相对罕见的鼻窦恶性组织学类型的病例。从这些分析中已收集到了具有临床实用价值的参数。应考虑到一些重要的局限性，如化疗数据的遗漏、所采用的手术方式、放疗类型以及选择和混杂偏倚等。尽管如此，基于人群的分析为临床医生提供了关于鼻窦恶性肿瘤管理方面易于推广且具有临床相关性的信息。
