Park Sung Yool, Jung Sung Ha, Seo Anna, Noh Hakjong, Lee Hwansun, Kim Hyo Jun, Kim Younghac, Chung Man Ki, Jeong Han-Sin, Baek Chung-Hwan, Son Young-Ik, Choi Nayeon
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Busan Paik Hospital, Inje University, Busan 47392, Republic of Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Republic of Korea.
Cancers (Basel). 2025 Jan 4;17(1):140. doi: 10.3390/cancers17010140.
This study evaluates the impact of three-dimensional (3D) printing-guided maxillectomy compared with conventional maxillectomy on surgical precision and oncological outcomes in patients with head and neck cancer.
A retrospective analysis was conducted on 42 patients undergoing maxillectomy (16 in a 3D printing-guided group and 26 in a conventional group). Patient demographics, tumor characteristics, and outcomes were compared. Survival outcomes were analyzed using the Kaplan-Meier method.
The 3D printing group showed higher rates of negative resection margins (81.3% vs. 76.9%) compared with the conventional group and a trend toward improved 5-year local recurrence-free survival (87.5% vs. 58.7%, respectively) and overall survival (84.4% vs. 70.1%, respectively). However, the differences were not statistically significant.
Maxillectomy guided by 3D printing may offer enhanced surgical precision and improved local control in patients undergoing head and neck cancer surgeries. Further research with larger cohorts is necessary to confirm these findings.
本研究评估了三维（3D）打印引导的上颌骨切除术与传统上颌骨切除术相比，对头颈癌患者手术精度和肿瘤学结局的影响。
对42例行上颌骨切除术的患者进行回顾性分析（3D打印引导组16例，传统组26例）。比较患者人口统计学、肿瘤特征和结局。采用Kaplan-Meier法分析生存结局。
与传统组相比，3D打印组的切缘阴性率更高（分别为81.3%和76.9%），且有5年局部无复发生存率提高（分别为87.5%和58.7%）和总生存率提高（分别为84.4%和70.1%）的趋势。然而，差异无统计学意义。
3D打印引导的上颌骨切除术可能会提高头颈癌手术患者的手术精度并改善局部控制。需要更大样本量的进一步研究来证实这些发现。
