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关节腔内左旋布比卡因与左旋布比卡因加硫酸镁对关节镜下半月板切除术患者术后镇痛的影响:一项前瞻性随机对照研究。

The effects of intra-articular levobupivacain versus levobupivacain plus magnesium sulfate on postoperative analgesia in patients undergoing arthroscopic meniscectomy: A prospective randomized controlled study.

作者信息

Kızılcık Nurcan, Özler Turhan, Menda Ferdi, Uluçay Çağatay, Köner Özge, Altıntaş Faik

机构信息

Yeditepe University Faculty of Medicine, Turkey.

Yeditepe University Faculty of Medicine, Turkey.

出版信息

Acta Orthop Traumatol Turc. 2017 Mar;51(2):104-109. doi: 10.1016/j.aott.2017.02.014. Epub 2017 Mar 15.

DOI:10.1016/j.aott.2017.02.014
PMID:28314555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6197358/
Abstract

OBJECTIVE

The aim of this study was to compared the effectiveness of intraarticular levobupivacain with levobupivacain and magnesium sulfate.

METHODS

In this prospective randomized double blinded study, 96 patients (67 male, 29 female; age range: 18-65 years) with ASA (American Society of Anesthesiologist) score I and II, who had undergone arthroscopic meniscectomy operation, were divided to 3 groups that had postoperative analgesia with intra-articular saline injection (control group), levobupivacain injection (L group) or levobupivacain and magnesium sulfate injection (LM group). Patients were compared with postoperative VAS (Visual Analog Score) score during rest and activity, opioid analgesic need, non-opioid analgesic need and other medication needs.

RESULTS

Postoperative VAS scores during rest and activation at early postoperative period were significantly lower at LM group when compared with L group and lower than control group at all time periods. Opioid analgesic need, non-opioid analgesic need and other medication needs for non-pain symptoms were lower at LM group when compared with L and control groups at all time periods.

CONCLUSION

Intraarticular magnesium sulfate plus Levobupivacain injection is a safe and effective method for post operative pain management after arthroscopic meniscectomy.

摘要

目的

本研究旨在比较关节腔内注射左旋布比卡因与左旋布比卡因和硫酸镁联合使用的效果。

方法

在这项前瞻性随机双盲研究中,96例美国麻醉医师协会(ASA)分级为I级和II级、接受关节镜半月板切除术的患者(67例男性,29例女性;年龄范围:18 - 65岁)被分为3组,分别接受关节腔内注射生理盐水(对照组)、左旋布比卡因注射(L组)或左旋布比卡因和硫酸镁注射(LM组)进行术后镇痛。比较患者术后静息和活动时的视觉模拟评分(VAS)、阿片类镇痛药需求、非阿片类镇痛药需求及其他药物需求。

结果

与L组相比,LM组术后早期静息和活动时的VAS评分显著更低,且在所有时间段均低于对照组。在所有时间段,LM组的阿片类镇痛药需求、非阿片类镇痛药需求及非疼痛症状的其他药物需求均低于L组和对照组。

结论

关节腔内注射硫酸镁加左旋布比卡因是关节镜半月板切除术后疼痛管理的一种安全有效的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0a8/6197358/ca80dd537305/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0a8/6197358/8e259b7110e3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0a8/6197358/b53916cd512a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0a8/6197358/dce641cfc5a4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0a8/6197358/ca80dd537305/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0a8/6197358/8e259b7110e3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0a8/6197358/b53916cd512a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0a8/6197358/dce641cfc5a4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0a8/6197358/ca80dd537305/gr4.jpg

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