Carniel Emanuele Luigi, Frigo Alessandro, Fontanella Chiara Giulia, De Benedictis Giulia Maria, Rubini Alessandro, Barp Luca, Pluchino Gioela, Sabbadini Beatrice, Polese Lino
Department of Industrial Engineering, University of Padova, Via Venezia 1, I-35131 Padova, Italy; Centre for Mechanics of Biological Materials, University of Padova, Via F. Marzolo 9, I-35131 Padova, Italy.
Department of Industrial Engineering, University of Padova, Via Venezia 1, I-35131 Padova, Italy; Centre for Mechanics of Biological Materials, University of Padova, Via F. Marzolo 9, I-35131 Padova, Italy.
J Biomech. 2017 May 3;56:32-41. doi: 10.1016/j.jbiomech.2017.02.029. Epub 2017 Mar 4.
Bariatric surgery includes a variety of procedures that are performed on obese people and aim at decreasing the intake of food and calories. This goal is usually pursued by reducing stomach capacity and/or absorbing capability. Adjustable gastric banding is the most common and successful operation. In general, bariatric surgical procedures are effective, but are often associated with major complications. Surgical procedure and post-surgical conformation of the stomach are usually defined on clinical and surgical basis only. Instead, the optimal configuration should be identified by analyzing the mechanical functionality of the stomach and the surrounding structures, and the relationship between food intake, nutrient adsorption, mechanical stimulation of stomach wall and feeling of satiety. A novel approach to bariatric surgery is required, integrating competences in the areas of biomechanics, physiology and surgery, based on a strong interaction between engineers and clinicians. Preliminary results from coupled experimental and computational investigations are here reported. The analyses aim to develop computational tools for the investigation of stomach mechanical functionality in pre- and post-surgical conformations.
减肥手术包括对肥胖人群实施的多种手术程序，旨在减少食物和热量的摄入量。这个目标通常通过减小胃容量和/或吸收能力来实现。可调节胃束带术是最常见且成功的手术。一般来说，减肥手术程序是有效的，但常常伴有严重并发症。胃的手术程序和术后形态通常仅在临床和手术基础上确定。相反，最佳形态应通过分析胃及周围结构的机械功能，以及食物摄入、营养吸收、胃壁机械刺激和饱腹感之间的关系来确定。需要一种新的减肥手术方法，基于工程师和临床医生之间的紧密互动，整合生物力学、生理学和外科学领域的专业知识。本文报告了耦合实验和计算研究的初步结果。这些分析旨在开发计算工具，用于研究手术前后形态下胃的机械功能。
