• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

垂体炎:免疫相关不良事件的护理管理

Hypophysitis: Nursing Management of Immune-Related Adverse Events
.

作者信息

Vazquez Adrienne

机构信息

University of Miami.

出版信息

Clin J Oncol Nurs. 2017 Apr 1;21(2):154-156. doi: 10.1188/17.CJON.154-156.

DOI:10.1188/17.CJON.154-156
PMID:28315541
Abstract

Immunotherapy can treat cancer and prevent future cancer relapse by enhancing the body's immune system. With novel immunotherapeutic agents like checkpoint inhibitors come unique immune-related adverse events. Hypophysitis, one of the lesser known immune-related complications, may be observed in patients receiving checkpoint inhibitors. Although the acute symptoms of immune-related hypophysitis may be managed with attentive monitoring and high-dose corticosteroids, lifelong hormone substitution therapy may be warranted. Oncology nurses are responsible for educating themselves and their patients on the complications of immunotherapy.
.

摘要

免疫疗法可以通过增强人体免疫系统来治疗癌症并预防未来癌症复发。随着检查点抑制剂等新型免疫治疗药物的出现,出现了独特的免疫相关不良事件。垂体炎是一种鲜为人知的免疫相关并发症,在接受检查点抑制剂治疗的患者中可能会出现。尽管免疫相关垂体炎的急性症状可以通过密切监测和大剂量皮质类固醇进行处理,但可能需要终身激素替代治疗。肿瘤学护士有责任让自己和患者了解免疫疗法的并发症。

相似文献

1
Hypophysitis: Nursing Management of Immune-Related Adverse Events
.垂体炎:免疫相关不良事件的护理管理
Clin J Oncol Nurs. 2017 Apr 1;21(2):154-156. doi: 10.1188/17.CJON.154-156.
2
Immune checkpoint inhibitor therapy-induced hypophysitis ∼ a case series of Taiwanese patients.免疫检查点抑制剂治疗引起的垂体炎。台湾患者的病例系列。
J Formos Med Assoc. 2019 Jan;118(1 Pt 3):524-529. doi: 10.1016/j.jfma.2018.07.014. Epub 2018 Aug 10.
3
Immune checkpoint inhibitor-related hypophysitis and endocrine dysfunction: clinical review.免疫检查点抑制剂相关垂体炎和内分泌功能障碍:临床综述
Clin Endocrinol (Oxf). 2016 Sep;85(3):331-9. doi: 10.1111/cen.13063. Epub 2016 Apr 13.
4
Pituitary enlargement following ipilimumab without long term endocrine dysfunction.使用依匹单抗后出现垂体增大,但无长期内分泌功能障碍。
Curr Probl Cancer. 2021 Dec;45(6):100710. doi: 10.1016/j.currproblcancer.2021.100710. Epub 2021 Feb 10.
5
[Lymphocytic hypophysitis due to ipilimumap therapy].[因伊匹单抗治疗导致的淋巴细胞性垂体炎]
Ugeskr Laeger. 2012 Jun 25;174(26):1829-30.
6
Endocrine-related adverse events associated with immune-checkpoint inhibitors in patients with melanoma.黑色素瘤患者使用免疫检查点抑制剂相关的内分泌不良反应。
Cancer Med. 2019 Nov;8(15):6585-6594. doi: 10.1002/cam4.2533. Epub 2019 Sep 13.
7
Hypophysitis on immunotherapy with checkpoint inhibitors.免疫检查点抑制剂免疫治疗相关的垂体炎
J Dtsch Dermatol Ges. 2019 Nov;17(11):1168-1170. doi: 10.1111/ddg.13963. Epub 2019 Nov 7.
8
[Ipilimumab-induced hypophysitis].[伊匹单抗诱发的垂体炎]
Rofo. 2013 Mar;185(3):268-9. doi: 10.1055/s-0032-1325515. Epub 2012 Nov 15.
9
Systemic high-dose corticosteroid treatment does not improve the outcome of ipilimumab-related hypophysitis: a retrospective cohort study.全身大剂量皮质类固醇治疗不能改善与伊匹单抗相关的垂体炎的预后:一项回顾性队列研究。
Clin Cancer Res. 2015 Feb 15;21(4):749-55. doi: 10.1158/1078-0432.CCR-14-2353. Epub 2014 Dec 23.
10
Nivolumab-induced hypophysitis in a patient with advanced malignant melanoma.一名晚期恶性黑色素瘤患者出现的纳武单抗诱发的垂体炎。
Endocr J. 2016 Oct 29;63(10):905-912. doi: 10.1507/endocrj.EJ16-0161. Epub 2016 Jul 20.

引用本文的文献

1
Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline.免疫检查点抑制剂治疗患者免疫相关不良反应的管理:美国临床肿瘤学会临床实践指南。
J Clin Oncol. 2018 Jun 10;36(17):1714-1768. doi: 10.1200/JCO.2017.77.6385. Epub 2018 Feb 14.