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桥本甲状腺炎(HT)概述以及碘、硒、维生素D和麸质对HT患者自身免疫和饮食管理的重要性。尚需进一步研究的要点。

A concise review of Hashimoto thyroiditis (HT) and the importance of iodine, selenium, vitamin D and gluten on the autoimmunity and dietary management of HT patients.Points that need more investigation.

作者信息

Liontiris Michael I, Mazokopakis Elias E

机构信息

Department of Internal Medicine, Naval Hospital of Crete, Chania, Greece.

出版信息

Hell J Nucl Med. 2017 Jan-Apr;20(1):51-56. doi: 10.1967/s002449910507. Epub 2017 Mar 20.

Abstract

Hashimoto's thyroiditis (HT) is a chronic autoimmune thyroid disease caused by an interaction between genetic factors and environmental conditions, both of which are yet to be fully understood. The management of HT depends on its clinical manifestations, commonly including diffuse or nodular goiter with euthyroidism, subclinical hypothyroidism and permanent hypothyroidism. However, in most cases of patients with HT, lifelong levothyroxine substitution is required. The additional role of diet for the management of HT is usually overlooked. A literature search regarding the importance and the influence of iodine, selenium, vitamin D and gluten on HT was conducted. In HT careful supplementation of possible deficiencies is recommended for the dietary management of these patients. The use of a diet low in gluten among HT patients with or without celiac disease (CD) is discussed.

摘要

桥本甲状腺炎(HT)是一种慢性自身免疫性甲状腺疾病,由遗传因素与环境因素相互作用引起,而这两者目前尚未被完全了解。HT的治疗取决于其临床表现,常见的表现包括伴有甲状腺功能正常的弥漫性或结节性甲状腺肿、亚临床甲状腺功能减退和永久性甲状腺功能减退。然而,在大多数HT患者中,需要终身服用左甲状腺素进行替代治疗。饮食在HT治疗中的额外作用通常被忽视。我们对碘、硒、维生素D和麸质对HT的重要性及影响进行了文献检索。对于这些患者的饮食管理,建议在HT患者中仔细补充可能存在的缺乏物质。本文还讨论了在患有或未患有乳糜泻(CD)的HT患者中使用低麸质饮食的情况。

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