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镫骨切除术后肉芽肿:一种严重的并发症。

Post-stapedectomy granuloma: a devastating complication.

作者信息

Watts E, Powell H R F, Saeed S R, Irving R M

机构信息

ENT Department,Queen Elizabeth Hospital Birmingham,UK.

ENT Department,Royal National Throat, Nose and Ear Hospital,London,UK.

出版信息

J Laryngol Otol. 2017 Jun;131(6):557-560. doi: 10.1017/S0022215117000627. Epub 2017 Mar 20.

Abstract

OBJECTIVES

This paper reports three cases of severe post-stapedectomy granuloma, emphasising the variable presentation of this devastating complication and the challenges of its management.

METHODS

A retrospective review was conducted of three cases of post-stapedectomy granuloma requiring surgical debulking between 2010 and 2015. Clinical symptoms, serial imaging, histopathology and post-operative outcomes were considered.

RESULTS

Intra-operatively, extensive granulation tissue with erosion of the otic capsule was found. There was spread along the VIIth and VIIIth cranial nerves to the cochlear nucleus in one patient. Post-operative clinical improvement was demonstrable, corroborated by diminution of contrast enhancement on serial magnetic resonance imaging. Facial nerve function recovered, tinnitus amelioration was variable and some otalgia persisted. Post-operative complications included grade IV facial weakness and late Pseudomonas aeruginosa meningitis, which all resolved.

CONCLUSION

To the authors' knowledge, this paper reports the only case of post-stapedectomy granuloma tracking to the brainstem. Otalgia was present in all our cases, and may be deemed a red flag symptom of progressive bony destruction and otic capsule involvement. Although granuloma remains rare, it should be considered in any patient with worsening otological symptoms following stapes surgery.

摘要

目的

本文报告三例严重的镫骨切除术后肉芽肿病例,强调这种破坏性并发症的多样表现及其治疗挑战。

方法

对2010年至2015年间三例需要手术切除的镫骨切除术后肉芽肿病例进行回顾性研究。考虑了临床症状、系列影像学检查、组织病理学和术后结果。

结果

术中发现广泛的肉芽组织伴听囊侵蚀。一名患者的肉芽组织沿第七和第八颅神经蔓延至蜗神经核。术后临床症状改善明显,系列磁共振成像显示对比增强减弱证实了这一点。面神经功能恢复,耳鸣改善情况不一,仍有一些耳痛持续存在。术后并发症包括IV级面神经麻痹和晚期铜绿假单胞菌脑膜炎,均已痊愈。

结论

据作者所知,本文报告了唯一一例追踪至脑干的镫骨切除术后肉芽肿病例。我们所有病例均有耳痛,可被视为进行性骨质破坏和听囊受累的警示症状。虽然肉芽肿仍然罕见,但在任何镫骨手术后耳科症状恶化的患者中都应考虑到这一情况。

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