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飞秒激光技术用于圆锥角膜眼植入MyoRing的临床结果

Clinical outcomes of MyoRing implantation in keratoconic eyes by using the Femtosecond laser technology.

作者信息

Nasrollahi K, Rezaei L, Ghoreishi M, Kashfi A, Mahboubi M

机构信息

Isfahan University of Medical Sciences, Isfahan, Iran.

Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

J Med Life. 2015;8(Spec Iss 3):66-71.

PMID:28316668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5348932/
Abstract

To assess the outcomes of the insertion of the MyoRing (DIOPTEX, GMBH, Linz, Austria) by applying the Femtosecond Laser Technology (FLT) method in eyes that have keratoconus problem. A prospective, nonrandomized, clinical examination was managed. 27 eyes of 15 subjects with stable keratoconus (6 females and 9 males), with lifetimes differing from 14 to 49 years were involved. All subjects have problems about decreased fine-accurate ocular awareness, lens intolerantness or trouble, and also the middle corneal height larger than 350 micrometers. MyoRing additions of about 320 micrometers into height and 2.5 mm into radius were inserted in each subject inside an Intrastromal Corneal Pocket using(ICP) formed with applying FLT. Ocular, refractive errors, corneal shape, and pachymetry changes were assessed throughout a 6-months follow-up period. The average UDVA (uncorrected distance visual acuity) notably increased originating at 1.73 ± 0.53 LogMAR preoperationally to 0.54 ± 0.40 LogMAR post-operationally. The average CDVA (corrected distance ocular awareness) notably increased from 0.59 ± 0.47 LogMAR preoperationally to 0.27 ± 0.16 LogMAR post-operationally. The change in the average UDVA and CDVA was analytically meaningful (P< 0.000). The average reduction in the average keratometry from preoperational to 26 weeks post operational was -6.41 ± 3.62 D. This change was analytically meaningful (P< 0.000). The average lowest and highest keratometry amounts were similarly analytically notable at shorter than 26 weeks preoperatively. A notable increase in UDVA and CDVA was observed 26 weeks following the operation, that was compatible with the notable decrease in sphere and cylinder. Moreover, a notable corneal straightening with an average amount of -6.41 ± 3.62 diopters (D) was determined. MyoRing implantation employing FLT would be a harmless, effective, and predictable method to treat selected subjects of keratoconus, being a helpful choice for the therapy of keratoconus.

摘要

为评估在患有圆锥角膜问题的眼睛中应用飞秒激光技术(FLT)方法植入MyoRing(DIOPTEX,GMBH,奥地利林茨)的效果。进行了一项前瞻性、非随机的临床检查。纳入了15名患有稳定圆锥角膜的受试者的27只眼睛(6名女性和9名男性),年龄在14至49岁之间。所有受试者均存在精细准确的眼部感知下降、镜片不耐受或不适问题,且角膜中央高度大于350微米。使用FLT形成的基质内角膜袋(ICP),在每个受试者的基质内角膜袋中植入高度约320微米、半径2.5毫米的MyoRing。在6个月的随访期内评估眼部、屈光不正、角膜形状和角膜厚度变化。平均未矫正远视力(UDVA)从术前的1.73±0.53 LogMAR显著提高到术后的0.54±0.40 LogMAR。平均矫正远视力(CDVA)从术前的0.59±0.47 LogMAR显著提高到术后的0.27±0.16 LogMAR。平均UDVA和CDVA的变化具有统计学意义(P<0.000)。术前到术后26周,平均角膜曲率的平均降低为-6.41±3.62 D。这一变化具有统计学意义(P<0.000)。术前短于26周时,平均最低和最高角膜曲率值同样具有统计学显著性。术后26周观察到UDVA和CDVA显著增加,这与球镜和柱镜的显著降低相一致。此外,确定角膜平均有-6.41±3.62屈光度(D)的显著变平。采用FLT植入MyoRing将是一种安全、有效且可预测的治疗圆锥角膜特定受试者的方法,是圆锥角膜治疗的一个有益选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d8a/5348932/4f69ffa836ab/SIJMedLife-08-03-66-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d8a/5348932/4f69ffa836ab/SIJMedLife-08-03-66-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d8a/5348932/4f69ffa836ab/SIJMedLife-08-03-66-g001.jpg

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本文引用的文献

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Femtosecond laser-assisted implantation of complete versus incomplete rings for keratoconus treatment.飞秒激光辅助植入完整与不完整角膜环治疗圆锥角膜
Clin Ophthalmol. 2015 Jan 20;9:121-7. doi: 10.2147/OPTH.S73855. eCollection 2015.
2
Femtosecond laser-assisted MyoRing implantation in postoperative LASIK ectasia.飞秒激光辅助 MyoRing 植入术治疗 LASIK 术后扩张性角膜病变。
J Refract Surg. 2014 Jul;30(7):462-6. doi: 10.3928/1081597X-20140521-02. Epub 2014 May 28.
3
Implantation of a complete intrastromal corneal ring at 2 different stromal depths in keratoconus.
在圆锥角膜中于 2 种不同的基质深度植入完整的基质内角膜环。
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