Pozharisskiĭ K M, Nikitin A Iu
Vopr Onkol. 1988;34(2):204-8.
The microscopic structure of tumors induced in rats by subcutaneous injections of 7,12-dimethylbenz(a) anthracene (DMBA) was studied. Most of them (90%) were histologically identical to malignant fibrous histiocytoma (MFH) in humans. This experimental model is useful in MFH morphogenesis and histogenesis studies in connection with the high frequency and synchronicity of tumor development and distinct localization of tumor at the site of injection.
研究了通过皮下注射7,12 - 二甲基苯并(a)蒽（DMBA）诱导大鼠产生的肿瘤的微观结构。其中大多数（90%）在组织学上与人类恶性纤维组织细胞瘤（MFH）相同。鉴于肿瘤发生的高频率和同步性以及肿瘤在注射部位的明显定位，该实验模型在MFH形态发生和组织发生研究中很有用。
