Boiko Ernest V, Maltsev Dmitrii S
St. Petersburg Branch of the Academician S. Fyodorov IRTC "Eye Microsurgery", 21 Yaroslav Gashek St., Saint Petersburg 192283, Russia; Department of Ophthalmology, Mechnikov North-West State Medical University, 47 Kirochnaya St., Saint Petersburg 191015, Russia; Department of Ophthalmology, Military Medical Academy, 5 Klinicheskaya St., Saint Petersburg 194044, Russia.
Department of Ophthalmology, Military Medical Academy, 5 Klinicheskaya St., Saint Petersburg 194044, Russia.
J Ophthalmol. 2017;2017:7656418. doi: 10.1155/2017/7656418. Epub 2017 Feb 20.
. To compare the controllability of navigated macular laser photocoagulation (MLP) in dry versus edematous retina and validate that pretreatment diagnostic images can be used as basis for navigated MLP after the macular edema (ME) has been resolved. . Group 1 was divided into subgroup 1 (dry retina MLP) and subgroup 2 (MLP in ME) for comparisons of laser-burn diameters. In group 2, the areas and locations of ME before an intravitreal injection of anti-VEGF (IVAV) were compared with those of recurrent ME. . The average actual diameter as percentage of planned diameter of laser burn in subgroup 1 (11 DME eyes, 6 BRVO eyes) versus subgroup 2 (5 DME eyes, 8 BRVO eyes) was 115.1 ± 9.1% versus 167.2 ± 13.8% (based on retro-mode scanning laser ophthalmoscopy), and 118.1 ± 14.8% versus 176.1 ± 11.6% (based on OCT) ( < 0.001). In group 2 (6 DME eyes, 6 BRVO eyes), difference in mean ME area before IVAV and that in recurrent edema was insignificant ( > 0.05). . The controllability of navigated MLP in dry retina is improved compared to edematous retina. This study validates that pretreatment diagnostic images can be used as basis for navigated MLP after the edema has been resolved.
比较导航式黄斑激光光凝术（MLP）在干性视网膜与水肿性视网膜中的可控性，并验证黄斑水肿（ME）消退后，预处理诊断图像可作为导航式MLP的基础。第1组分为亚组1（干性视网膜MLP）和亚组2（ME中的MLP），以比较激光烧灼直径。在第2组中，比较玻璃体内注射抗VEGF（IVAV）前ME的面积和位置与复发性ME的面积和位置。亚组1（11只糖尿病性黄斑水肿（DME）眼，6只视网膜分支静脉阻塞（BRVO）眼）与亚组2（5只DME眼，8只BRVO眼）中激光烧灼的平均实际直径占计划直径的百分比，基于视网膜逆向扫描激光检眼镜检查分别为115.1±9.1%和167.2±13.8%，基于光学相干断层扫描（OCT）分别为118.1±14.8%和176.1±11.6%（P<0.001）。在第2组（6只DME眼，6只BRVO眼）中，IVAV前平均ME面积与复发性水肿的平均ME面积差异无统计学意义（P>0.05）。与水肿性视网膜相比，导航式MLP在干性视网膜中的可控性得到改善。本研究验证了水肿消退后，预处理诊断图像可作为导航式MLP的基础。
