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卡介苗治疗后发生的霉菌性动脉瘤:病例报告及文献复习

Mycotic Aneurysm after Bacillus Calmette-Guérin Treatment: Case Report and Review of the Literature.

作者信息

Coddington Nathaniel D, Sandberg Jesse K, Yang Chen, Sehn Jennifer K, Kim Eric H, Strope Seth A

机构信息

Washington University School of Medicine in St. Louis, St. Louis, MO, USA.

出版信息

Case Rep Urol. 2017;2017:4508583. doi: 10.1155/2017/4508583. Epub 2017 Feb 20.

DOI:10.1155/2017/4508583
PMID:28316859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5337836/
Abstract

. Intravesicular Bacillus Calmette-Guérin (BCG) is an effective adjunctive therapy for superficial bladder cancer that has been shown to delay recurrence and progression of disease. Serious side effects are relatively rare but are difficult to diagnosis and commonly overlooked. . We report the case of a patient who was found to have mycotic aortic aneurysms secondary to treatment with BCG after a prolonged course with multiple intervening hospitalizations. . Through this report, we discuss our present understanding of BCG infection following treatment and review the literature regarding this particular rare manifestation.

摘要

膀胱内灌注卡介苗(BCG)是浅表性膀胱癌的一种有效辅助治疗方法,已被证明可延缓疾病的复发和进展。严重副作用相对少见,但难以诊断且常被忽视。我们报告一例患者,在经历了漫长病程并多次住院治疗后,因卡介苗治疗继发霉菌性主动脉瘤。通过本报告,我们讨论目前对卡介苗治疗后感染的认识,并回顾关于这种特殊罕见表现的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5337836/d80a7f7731cb/CRIU2017-4508583.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5337836/5f8baa768dca/CRIU2017-4508583.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5337836/d80a7f7731cb/CRIU2017-4508583.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5337836/5f8baa768dca/CRIU2017-4508583.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca70/5337836/d80a7f7731cb/CRIU2017-4508583.002.jpg

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J Vasc Surg Cases Innov Tech. 2022 Nov 8;8(4):807-812. doi: 10.1016/j.jvscit.2022.10.020. eCollection 2022 Dec.
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本文引用的文献

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BCG-osis following intravesical BCG treatment leading to miliary pulmonary nodules, penile granulomas and a mycotic aortic aneurysm.膀胱内卡介苗治疗后发生卡介苗病,导致粟粒性肺结节、阴茎肉芽肿和霉菌性主动脉瘤。
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Successful treatment of a mycotic multifocal thoracoabdominal aortic aneurysm as a late sequelae of intravesical bacillus Calmette-Guerin therapy: case report and literature review.卡介苗膀胱内灌注治疗后迟发性后遗症——真菌性多灶性胸腹主动脉瘤的成功治疗:病例报告及文献综述
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Therapeutic effectiveness of tuberculous aneurysm and risk factors for mortality: a systematic review.
结核性动脉瘤的治疗效果和死亡风险因素:系统评价。
Gen Thorac Cardiovasc Surg. 2022 Jun;70(6):515-525. doi: 10.1007/s11748-022-01811-9. Epub 2022 Apr 4.
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Mycotic infrarenal aortic aneurysm due to mycobacterium after intravesical treatment for bladder cancer.膀胱癌膀胱内治疗后由分枝杆菌引起的霉菌性肾下腹主动脉瘤。
J Vasc Surg Cases Innov Tech. 2021 Mar 2;7(2):354-356. doi: 10.1016/j.jvscit.2021.02.011. eCollection 2021 Jun.
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Aortic aneurysm and aortic graft infection related to Mycobacterium bovis after intravesical Bacille Calmette-Guérin therapy-a case series.膀胱内卡介苗治疗后与牛分枝杆菌相关的主动脉瘤和主动脉移植物感染:病例系列。
BMC Surg. 2021 Mar 17;21(1):138. doi: 10.1186/s12893-021-01142-1.
Bacillus Calmette-Guérin (BCG) infection following intravesical BCG administration as adjunctive therapy for bladder cancer: incidence, risk factors, and outcome in a single-institution series and review of the literature.
卡介苗(BCG)膀胱内灌注作为膀胱癌辅助治疗后的感染:单中心系列研究中的发病率、危险因素及结局,并对文献进行综述
Medicine (Baltimore). 2014 Oct;93(17):236-254. doi: 10.1097/MD.0000000000000119.
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Fever of unknown origin and pancytopenia caused by culture-proven delayed onset disseminated bacillus Calmette-Guerin (BCG) infection after intravesical instillation.膀胱内灌注后经培养证实的迟发性播散性卡介苗(BCG)感染所致不明原因发热和全血细胞减少。
BMJ Case Rep. 2013 Apr 9;2013:bcr2013008949. doi: 10.1136/bcr-2013-008949.
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Intravesical Bacillus Calmette-Guerin in Ta and T1 Bladder Cancer.卡介苗膀胱灌注治疗Ta和T1期膀胱癌
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Prog Clin Biol Res. 1989;310:325-34.