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静脉闭塞治疗患者的近红外荧光淋巴成像

Near-infrared fluorescence lymphatic imaging in a patient treated for venous occlusion.

作者信息

Rasmussen John C, Aldrich Melissa B, Guilliod Renie, Fife Caroline E, O'Donnell Thomas F, Sevick-Muraca Eva M

机构信息

The University of Texas Health Science Center at Houston, Houston, TX.

The University of Texas Health Science Center at Houston, Houston, TX; Memorial Hermann Hospital, Houston, TX.

出版信息

J Vasc Surg Cases. 2015 Sep;1(3):201-204. doi: 10.1016/j.jvsc.2015.05.004.

DOI:10.1016/j.jvsc.2015.05.004
PMID:28317008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5356231/
Abstract

Although lower extremity edema/lymphedema can result from venous and/or lymphatic abnormalities, effective treatment depends upon understanding their relative contributions to the condition. Herein we use near-infrared fluorescence lymphatic imaging in a 16 year-old female diagnosed with unilateral lymphedema of the right leg and previously treated with left iliac vein stenting in an attempt to alleviate lymphedema. The imaging shows that abnormal lymphatic anatomy, rather than venous occlusion, was likely responsible for unilateral swelling.

摘要

虽然下肢水肿/淋巴水肿可能由静脉和/或淋巴异常引起,但有效的治疗取决于了解它们对病情的相对影响。在此,我们对一名16岁女性进行了近红外荧光淋巴成像检查,该女性被诊断为右腿单侧淋巴水肿,此前曾接受左髂静脉支架置入术以缓解淋巴水肿。成像显示,异常的淋巴解剖结构而非静脉阻塞可能是单侧肿胀的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0704/8076959/0b2584896be9/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0704/8076959/ee65be651ed4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0704/8076959/0661b3025dde/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0704/8076959/0b2584896be9/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0704/8076959/ee65be651ed4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0704/8076959/0661b3025dde/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0704/8076959/0b2584896be9/gr3.jpg

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本文引用的文献

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Lymphatic abnormalities are associated with RASA1 gene mutations in mouse and man.淋巴异常与鼠和人中的 RASA1 基因突变有关。
Proc Natl Acad Sci U S A. 2013 May 21;110(21):8621-6. doi: 10.1073/pnas.1222722110. Epub 2013 May 6.
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Automated analysis of investigational near-infrared fluorescence lymphatic imaging in humans.人体研究性近红外荧光淋巴成像的自动化分析
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Indocyanine green (ICG) lymphography is superior to lymphoscintigraphy for diagnostic imaging of early lymphedema of the upper limbs.
吲哚菁绿(ICG)淋巴造影术优于淋巴闪烁显像术,可用于诊断上肢早期淋巴水肿。
PLoS One. 2012;7(6):e38182. doi: 10.1371/journal.pone.0038182. Epub 2012 Jun 4.
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VENOUS OBSTRUCTION IN THE AETIOLOGY OF LYMPHOEDEMA PRAECOX.早发性淋巴水肿病因中的静脉阻塞
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J Vasc Surg. 2001 Nov;34(5):779-84. doi: 10.1067/mva.2001.119396.
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Adv Drug Deliv Rev. 2001 Aug 23;50(1-2):3-20. doi: 10.1016/s0169-409x(01)00150-8.
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