Pharmacogenomic screening for anthracycline-induced cardiotoxicity in childhood cancer.
作者信息
Aminkeng Folefac, Ross Colin J D, Rassekh Shahrad R, Rieder Michael J, Bhavsar Amit P, Sanatani Shubhayan, Bernstein Daniel, Hayden Michael R, Amstutz Ursula, Carleton Bruce C
机构信息
Centre for Molecular Medicine and Therapeutics, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.
出版信息
Br J Clin Pharmacol. 2017 May;83(5):1143-1145. doi: 10.1111/bcp.13218. Epub 2017 Mar 19.
Abstract
摘要
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Recommendations for genetic testing to reduce the incidence of anthracycline-induced cardiotoxicity.关于基因检测以降低蒽环类药物所致心脏毒性发生率的建议。
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Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes.利用人类多能干细胞衍生的心肌细胞建立阿霉素诱导的心脏毒性模型。
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