Theiler Martin, Oza Vikash S, Mathes Erin F, Dvorak Christopher C, McCalmont Timothy H, Yeh Iwei, Sidbury Robert, Cordoro Kelly M
Department of Pediatric Dermatology, University Children's Hospital Zurich, Zurich, Switzerland.
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
Pediatr Dermatol. 2017 May;34(3):326-330. doi: 10.1111/pde.13108. Epub 2017 Mar 20.
Eosinophilic pustular folliculitis (EPF) is a rare cutaneous disorder that typically occurs in three clinical contexts: men, individuals who are immunosuppressed or have human immunodeficiency virus, and infants. A fourth subtype occurring 2 to 3 months after hematopoietic stem cell transplantation (HSCT) has recently been described in several adults. We report two cases of EPF arising in children after HSCT. It is important to recognize this form of EPF after HSCT and differentiate it from graft-versus-host disease since it responds readily to topical steroids and appears to have an excellent prognosis.
嗜酸性脓疱性毛囊炎（EPF）是一种罕见的皮肤疾病，通常发生在三种临床情况下：男性、免疫抑制或感染人类免疫缺陷病毒的个体以及婴儿。最近在一些成年人中描述了第四种亚型，其发生在造血干细胞移植（HSCT）后2至3个月。我们报告了两例HSCT后儿童发生的EPF病例。认识到HSCT后这种形式的EPF并将其与移植物抗宿主病区分开来很重要，因为它对局部类固醇反应良好，且预后似乎极佳。
