Goh Boon-Kee, Pandya Amit G
Skin Physicians Pte Ltd, 3 Mount Elizabeth, Suite 11-08 Mount Elizabeth Medical Centre, Singapore 228510, Singapore.
Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9069, USA.
Dermatol Clin. 2017 Apr;35(2):135-144. doi: 10.1016/j.det.2016.11.004.
Vitiligo has a variety of presentations, including focal, acrofacial, segmental, and generalized forms. Thorough knowledge of these presentations is important to make the correct diagnosis. Signs of activity are important to recognize so that treatment is optimized. Clinical findings of confettilike depigmentation, trichrome and inflammatory vitiligo, and the Koebner phenomenon should alert the clinician that a patient's disease is likely to worsen. These patients may require systemic treatment to stabilize their disease. Many other skin disorders present with hypopigmentation or depigmentation and must be distinguished to determine the right diagnosis, advise the patient on prognosis, and prescribe the correct treatment.
白癜风有多种表现形式，包括局限性、肢端颜面型、节段型和泛发型。全面了解这些表现形式对于做出正确诊断很重要。识别疾病活动迹象对于优化治疗很重要。点状样色素脱失、三色白癜风和炎症性白癜风以及同形反应的临床发现应提醒临床医生，患者的病情可能会恶化。这些患者可能需要系统治疗来稳定病情。许多其他皮肤疾病也会出现色素减退或色素脱失，必须加以区分以确定正确诊断、告知患者预后并开出正确的治疗方案。
