What's the Buzz About Hydroxynorketamine? Is It the History, the Story, the Debate, or the Promise?
作者信息
Abdallah Chadi G
机构信息
Clinical Neurosciences Division, National Center for PTSD, US Department of Veterans Affairs, West Haven; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
出版信息
Biol Psychiatry. 2017 Apr 15;81(8):e61-e63. doi: 10.1016/j.biopsych.2017.01.002.
Abstract
摘要
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本文引用的文献
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Reply to: Antidepressant Actions of Ketamine Versus Hydroxynorketamine.回复：氯胺酮与羟基去甲氯胺酮的抗抑郁作用
Biol Psychiatry. 2017 Apr 15;81(8):e69-e71. doi: 10.1016/j.biopsych.2016.08.039. Epub 2016 Sep 30.
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Antidepressant Actions of Ketamine Versus Hydroxynorketamine.氯胺酮与羟基去甲氯胺酮的抗抑郁作用
Biol Psychiatry. 2017 Apr 15;81(8):e65-e67. doi: 10.1016/j.biopsych.2016.06.029. Epub 2016 Sep 28.
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NMDAR inhibition-independent antidepressant actions of ketamine metabolites.氯胺酮代谢物的非NMDAR抑制依赖性抗抑郁作用。
Nature. 2016 May 26;533(7604):481-6. doi: 10.1038/nature17998. Epub 2016 May 4.
4
KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS.氯胺酮的作用机制：通往速效抗抑郁药之路。
Depress Anxiety. 2016 Aug;33(8):689-97. doi: 10.1002/da.22501. Epub 2016 Apr 6.
5
Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression.氯胺酮的血浆代谢物与重性抑郁反应、诊断和副作用的关系。
Biol Psychiatry. 2012 Aug 15;72(4):331-8. doi: 10.1016/j.biopsych.2012.03.004. Epub 2012 Apr 18.
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NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses.静息状态下 NMDA 受体阻断可迅速引发抗抑郁行为反应。
Nature. 2011 Jun 15;475(7354):91-5. doi: 10.1038/nature10130.
7
mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists.mTOR 依赖性突触形成是 NMDA 拮抗剂快速抗抑郁作用的基础。
Science. 2010 Aug 20;329(5994):959-64. doi: 10.1126/science.1190287.
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Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.氯胺酮抗抑郁作用的细胞机制：α-氨基-3-羟基-5-甲基异恶唑-4-丙酸受体的作用
Biol Psychiatry. 2008 Feb 15;63(4):349-52. doi: 10.1016/j.biopsych.2007.05.028. Epub 2007 Jul 23.
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Antidepressant effects of ketamine in depressed patients.氯胺酮对抑郁症患者的抗抑郁作用。
Biol Psychiatry. 2000 Feb 15;47(4):351-4. doi: 10.1016/s0006-3223(99)00230-9.
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Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression.抗抑郁治疗后N-甲基-D-天冬氨酸（NMDA）受体的适应性：对抑郁症药物治疗的启示。
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