Ogle Orrett E
Atlanta, GA, USA; Faculty of Medicine, Mona Dental Program, University of the West Indies, Kingston 6, Jamaica; Oral and Maxillofacial Surgery, Woodhull Hospital, 760 Broadway, Brooklyn, NY 11206, USA.
Dent Clin North Am. 2017 Apr;61(2):235-252. doi: 10.1016/j.cden.2016.11.004.
The pathogenesis of odontogenic infection is polymicrobial, consisting of various facultative and strict anaerobes. The dominant isolates are strictly anaerobic gram-negative rods and gram-positive cocci. The periapical infection is the most common form of odontogenic infection. Although odontogenic infections are usually confined to the alveolar ridge vicinity, they can spread into deep fascial spaces. Cavernous sinus thrombosis, brain abscess, airway obstruction, and mediastinitis are possible complications of dental infections. The most important element in treating odontogenic infections is elimination of the primary source of the infection with antibiotics as adjunctive therapy.
牙源性感染的发病机制是多微生物的,由各种兼性厌氧菌和严格厌氧菌组成。主要分离菌是严格厌氧的革兰氏阴性杆菌和革兰氏阳性球菌。根尖周感染是牙源性感染最常见的形式。虽然牙源性感染通常局限于牙槽嵴附近,但它们可扩散至深部筋膜间隙。海绵窦血栓形成、脑脓肿、气道阻塞和纵隔炎是牙科感染可能的并发症。治疗牙源性感染最重要的因素是消除感染的主要来源,并辅以抗生素治疗。