Simões Carla Regina Barbieri, Vassalo Flávia Gardilin, Lourenço Maria Lúcia Gomes, de Souza Fabiana Ferreira, Oba Eunice, Sudano Mateus José, Prestes Nereu Carlos
Department of Animal Reproduction, Universidade Estadual Paulista, UNESP, Botucatu, Sao Paulo, Brazil.
Department of Medical Clinic, Universidade Estadual Paulista, UNESP, Botucatu, Sao Paulo, Brazil.
Top Companion Anim Med. 2016 Dec;31(4):125-129. doi: 10.1053/j.tcam.2016.10.003. Epub 2016 Oct 26.
The objective of the study was to assess clinical alterations, electrocardiographic, hematological, biochemical, hemogasometric, electrolytic, and hormone plasma concentrations in bitches with eutocia and dystocia. Overall, 28 bitches (dystocia, n = 22 and eutocia, n = 6) were assessed. The evaluations were performed at 2 time points, M1 (1 hour prepartum-eutocia group and cesarean or clinical intervention-dystocia group) and M2 (postpartum-eutocia or dystocia group and anesthetic recovery-dystocia group). The main clinical finding was the hypothermia (mean: 36.9°C dystocia vs. 36.8°C eutocia). Sinus arrhythmia and tachycardia were the electrocardiographic parameters predominant in eutocia and sinus rhythm in dystocia group. The P wave amplitude, heart rate, creatinine concentration, hematocrit, and hemoglobin were increased in M1 (P < .05), whereas the concentration of TCO was higher in M2. There was an increase in P concentration in dystocia and total T concentrations were increased in M1 in both groups. Total T was higher in dystocia during M1 and in dystocia during M2 in eutocia than in dystocia. We concluded that at 1 hour prepartum or pre-cesarean, there is an increase in heart rate in bitches with eutocia or dystocia, and this finding was correlated to thyroid hormone concentration. P concentrations remained high during dystocia, and hematological and biochemical changes returned to normal after parturition. The evaluation of these parameters in pregnancy can be used as tool to prevent dystocia and consequent fetal death.
本研究的目的是评估顺产和难产母犬的临床改变、心电图、血液学、生化、血气分析、电解质及血浆激素浓度。总体上,共评估了28只母犬(难产22只,顺产6只)。评估在两个时间点进行,M1(分娩前1小时——顺产组和剖宫产或临床干预——难产组)和M2(产后——顺产或难产组以及麻醉苏醒——难产组)。主要临床发现是体温过低(平均:难产组36.9°C,顺产组36.8°C)。窦性心律失常和心动过速是顺产组主要的心电图参数,难产组以窦性心律为主。M1时P波振幅、心率、肌酐浓度、血细胞比容和血红蛋白升高(P<0.05),而M2时总二氧化碳(TCO)浓度较高。难产组磷(P)浓度升高,两组M1时总睾酮(T)浓度均升高。M1时难产组的总T高于顺产组,M2时顺产组难产过程中的总T高于难产组。我们得出结论,在分娩前1小时或剖宫产术前,顺产或难产母犬的心率升高,这一发现与甲状腺激素浓度相关。难产时P浓度持续升高,分娩后血液学和生化改变恢复正常。孕期对这些参数的评估可作为预防难产及随之而来的胎儿死亡的工具。