从扇叶棕榈（Borassus flabellifer Linn.）糖浆中分离出2,3,4-三羟基-5-甲基苯乙酮的首次报告及其抗氧化和抗菌特性。

First report on isolation of 2,3,4-trihydroxy-5-methylacetophenone from palmyra palm (Borassus flabellifer Linn.) syrup, its antioxidant and antimicrobial properties.

作者信息

Reshma M V, Jacob Jubi, Syamnath V L, Habeeba V P, Dileep Kumar B S, Lankalapalli Ravi S

机构信息

Agro-Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram 695019, Kerala, India.

出版信息

Food Chem. 2017 Aug 1;228:491-496. doi: 10.1016/j.foodchem.2017.02.043. Epub 2017 Feb 11.

DOI:10.1016/j.foodchem.2017.02.043

PMID:28317754

Abstract

The first report on isolation and characterization of 2,3,4-trihydroxy-5-methylacetophenone (1), nicotinamide (2), and uracil (3) from palmyra palm syrup is described. Total phenolic content (TPC) and Total flavonoid content (TFC) of palm syrup were 244.70±5.77(mggallic acid/kg of syrup) and 658.45±27.86(mg quercetin/kg of syrup), respectively. Compound 1 exhibited DPPH radical scavenging activity with an IC value of 20.02±0.14μM which was better than ascorbic acid (IC=22.59±0.30μM). Compound 1 also showed broad spectrum antibacterial activity against Escherichia coli, Mycobacterium smegmatis, Staphylococcus aureus and Staphylococcus simulans.

摘要

首次报道了从棕榈糖浆中分离和鉴定出2,3,4 - 三羟基 - 5 - 甲基苯乙酮（1）、烟酰胺（2）和尿嘧啶（3）。棕榈糖浆的总酚含量（TPC）和总黄酮含量（TFC）分别为244.70±5.77（mg没食子酸/千克糖浆）和658.45±27.86（mg槲皮素/千克糖浆）。化合物1表现出DPPH自由基清除活性，IC值为20.02±0.14μM，优于抗坏血酸（IC = 22.59±0.30μM）。化合物1还对大肠杆菌、耻垢分枝杆菌、金黄色葡萄球菌和模仿葡萄球菌表现出广谱抗菌活性。