Hu Yu, Chen Yaping, Wang Ying, Song Quanwei, Li Qian
a Institute of Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention , Binjiang District, Hangzhou , Zhejiang , China.
Hum Vaccin Immunother. 2017 Jun 3;13(6):1-8. doi: 10.1080/21645515.2017.1285476. Epub 2017 Feb 21.
To verify the effectiveness of prenatal vaccination education intervention on improving mother's vaccination knowledge and child's vaccination status in Zhejiang province, eastern China.
Pregnant women with ≥ 12 gestational weeks were recruited and randomly assigned into the intervention group and the control group. The intervention group were given a vaccination education session while the control group were not. Two round surveys were performed before and 3 months after the intervention. The vaccination status of child was extracted at 12 months of age from immunization information system. The differences of the vaccination knowledge, the coverage, the completeness and the timeliness of vaccination between 2 groups were evaluated. The effectiveness of vaccination education intervention was assessed, under the control of the other demographic variables.
Among the 1252 participants, 851 subjects replied to the post-survey. Significant improvements of vaccination knowledge between the pre- and the post- survey in the intervention group were observed (Mean ± S.D:1.8 ± 1.1 vs. 3.7 ± 1.2 for vaccines score and 2.7 ± 1.5 vs. 4.8 ± 1.0 for vaccine policy score, respectively). The coverage of fully vaccination was significantly higher in the intervention group (90.0% vs. 82.9%, P<0.01). The timeliness of fully vaccination was significantly higher in the intervention group (51.9% vs. 33.0%, P<0.01). In the intervention group, pregnant women were more likely to be with high score of knowledge (OR = 5.2, 95%CI: 2.6-8.8), and children were more likely to complete the full series of vaccination (OR = 3.4, 95%CI: 2.1-4.8), and children were more likely to complete the full series of vaccination in a timely manner (OR = 2.3, 95%CI: 1.6-3.5).
Vaccination education in the pregnant women can effectively improve the knowledge regarding immunization and increase the coverage, the completeness and the timeliness of childhood vaccination. Strong partnership needs to be established between the obstetricians and the vaccination staff to improve the performance of NIP.
验证产前疫苗接种教育干预对提高中国东部浙江省母亲的疫苗接种知识和儿童疫苗接种状况的有效性。
招募孕周≥12周的孕妇，随机分为干预组和对照组。干预组接受疫苗接种教育课程，对照组不接受。在干预前和干预后3个月进行两轮调查。从免疫信息系统中提取儿童12月龄时的疫苗接种状况。评估两组之间疫苗接种知识、接种覆盖率、完整性和及时性的差异。在控制其他人口统计学变量的情况下，评估疫苗接种教育干预的有效性。
在1252名参与者中，851名受试者回复了调查后问卷。干预组在调查前和调查后的疫苗接种知识有显著改善（疫苗得分分别为：均值±标准差：1.8±1.1对3.7±1.2，疫苗政策得分：2.7±1.5对4.8±1.0）。干预组全程接种覆盖率显著更高（90.0%对82.9%，P<0.01）。干预组全程接种及时性显著更高（51.9%对33.0%，P<0.01）。在干预组中，孕妇更有可能知识得分高（比值比=5.2，95%置信区间：2.6 - 8.8），儿童更有可能完成全程疫苗接种（比值比=3.4，95%置信区间：2.1 - 4.8），儿童更有可能及时完成全程疫苗接种（比值比=2.3，95%置信区间：1.6 - 3.5）。
对孕妇进行疫苗接种教育可有效提高免疫知识，并提高儿童疫苗接种的覆盖率、完整性和及时性。产科医生和疫苗接种工作人员之间需要建立强有力的合作关系，以提高国家免疫规划的绩效。
