From the *Department of Nuclear Medicine and Molecular Imaging, School of Medicine, Koc University; †Department of Nuclear Medicine and Molecular Imaging, VKF American Hospital; ‡Department of Urology, Koc University Hospital; and §Department of Pathology, School of Medicine, Acibadem University, Istanbul, Turkey.
Clin Nucl Med. 2017 May;42(5):403-405. doi: 10.1097/RLU.0000000000001617.
We aimed to emphasize how useful PSMA PET/CT findings can be while trying to restage prostate cancer after radical prostatectomy in the presence of low prostate-specific antigen values. A 64-year-old man with pT3b N1 M0 Gleason 7 adenocarcinoma of the prostate presented 5 years postoperatively with a palpable axillary mass, whereas his prostate-specific antigen was 0.08 ng/mL. Conventional imaging studies and histopathologic findings of the axillary mass biopsy revealed inconclusive results. Ga-PSMA PET/CT demonstrated PSMA-positive metastatic lesions, the largest one being located in the right axilla. This finding confirmed metastatic poorly differentiated prostate cancer, and androgen deprivation therapy was initiated.
我们旨在强调在前列腺特异性抗原（PSA）值较低的情况下，尝试对根治性前列腺切除术后的前列腺癌进行重新分期时，PSMA PET/CT 检查结果的实用性。一名 64 岁男性，前列腺腺癌 pT3bN1M0Gleason7 型，术后 5 年出现可触及的腋窝肿块，而他的 PSA 为 0.08ng/mL。常规影像学研究和腋窝肿块活检的组织病理学发现结果不确定。Ga-PSMA PET/CT 显示 PSMA 阳性的转移性病变，最大的一个位于右腋窝。这一发现证实了转移性低分化前列腺癌，并开始进行雄激素剥夺治疗。
