Omi Tsubasa, Ito Hiroshi, Riku Keisen, Kanai Koji, Takada Hiromune, Fujimi Satoshi, Matsunaga Hidenori, Ohi Kazutaka
Department of Psychiatry, Osaka General Medical Center, Osaka, Japan.
Department of Emergency Medicine, Osaka General Medical Center, Osaka, Japan.
BMC Psychiatry. 2017 Mar 20;17(1):99. doi: 10.1186/s12888-017-1267-5.
Patients with psychiatric disorders have a high rate of suicide. The present study investigated factors influencing hospital stays for Japanese patients with psychiatric disorders attempting suicide by jumping.
We diagnosed all suicide attempts (n = 113) by jumping based on the International Classification of Diseases 10th Revision (ICD-10) and investigated the mean hospital stays of patients with each diagnosis based on the ICD-10 code. We then analyzed differences in the demographic and clinical characteristics between the diagnostic groups to identify factors influencing the duration of hospital stay.
Patients diagnosed with schizophrenia (F2 code) were the most frequent (32.7%) of all diagnoses; therefore, we divided the diagnostic groups into schizophrenia group (n = 37) and other psychiatric diagnoses group (n = 76). The patients with schizophrenia showed a significantly longer hospital stay (125.7 ± 63.9 days) compared with the patients with other psychiatric diagnoses (83.6 ± 63.2) (β ± SE = 42.1 ± 12.7, p = 0.0013), whereas there was no difference in the jump height between the two groups (the average was the 3rd to 4th floor; p > 0.05). The number of injured parts, particularly lower-limb fractures, was significantly higher (p = 0.017) in patients with schizophrenia than in patients with other psychiatric diagnoses. The duration of psychiatric treatment in patients with schizophrenia were significantly longer (z = 3.4, p = 0.001) than in patients with other psychiatric diagnoses.
Our findings indicate that the number of injuries and the body parts injured in patients with schizophrenia are associated with a longer duration of hospital stay following a suicide attempt by jumping. The current use of antipsychotics and a longer duration of taking antipsychotics might contribute to the risk of bone fracture via hyperprolactinemia. Further cognitive impairment in patients with schizophrenia might prevent rehabilitation for the management of lower-limb fractures. From these results, we suggest that clinicians should monitor the level of prolactin and cognitive function in patients with schizophrenia in future studies on managing of lower-limb fractures.
精神疾病患者的自杀率很高。本研究调查了影响日本精神疾病患者跳楼自杀后住院时间的因素。
我们根据《国际疾病分类第10版》(ICD - 10)对所有跳楼自杀未遂事件(n = 113)进行诊断,并根据ICD - 10编码调查各诊断患者的平均住院时间。然后,我们分析了诊断组之间人口统计学和临床特征的差异,以确定影响住院时间的因素。
在所有诊断中,被诊断为精神分裂症(F2编码)的患者最为常见(32.7%);因此,我们将诊断组分为精神分裂症组(n = 37)和其他精神疾病诊断组(n = 76)。与其他精神疾病诊断患者(83.6 ± 63.2天)相比,精神分裂症患者的住院时间显著更长(125.7 ± 63.9天)(β ± SE = 42.1 ± 12.7,p = 0.0013),而两组之间的跳楼高度没有差异(平均为3楼至4楼;p > 0.05)。精神分裂症患者的受伤部位数量,尤其是下肢骨折,显著高于其他精神疾病诊断患者(p = 0.017)。精神分裂症患者的精神治疗时间显著长于其他精神疾病诊断患者(z = 3.4,p = 0.001)。
我们的研究结果表明,精神分裂症患者的受伤数量和受伤身体部位与跳楼自杀未遂后的住院时间延长有关。目前使用抗精神病药物以及服用抗精神病药物的时间较长可能通过高催乳素血症导致骨折风险增加。精神分裂症患者进一步的认知障碍可能会妨碍下肢骨折管理的康复。基于这些结果,我们建议临床医生在未来关于下肢骨折管理的研究中应监测精神分裂症患者的催乳素水平和认知功能。