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体外膜肺氧合期间对患者进行药物治疗：证据正在积累。

Medicating patients during extracorporeal membrane oxygenation: the evidence is building.

作者信息

Dzierba Amy L, Abrams Darryl, Brodie Daniel

机构信息

Columbia University Medical Center, Department of Pharmacy, NewYork-Presbyterian Hospital, New York, NY, 10032, USA.

Division of Pulmonary, Columbia University College of Physicians and Surgeons, Allergy and Critical Care, 622 West 168th Street, New York, NY, 10032, USA.

出版信息

Crit Care. 2017 Mar 21;21(1):66. doi: 10.1186/s13054-017-1644-y.

DOI:10.1186/s13054-017-1644-y
PMID:28320466
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5359850/
Abstract

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901 .

摘要

本文是从《2017年重症监护与急诊医学年度回顾》中选出的十篇综述之一。其他入选文章可在http://ccforum.com/series/annualupdate2017在线查看。有关《重症监护与急诊医学年度回顾》的更多信息可从http://www.springer.com/series/8901获取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85c2/5359850/26e1a27f1467/13054_2017_1644_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85c2/5359850/26e1a27f1467/13054_2017_1644_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85c2/5359850/26e1a27f1467/13054_2017_1644_Fig1_HTML.jpg

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Evaluation of sedatives, analgesics, and neuromuscular blocking agents in adults receiving extracorporeal membrane oxygenation.接受体外膜肺氧合的成人使用镇静剂、镇痛药和神经肌肉阻滞剂的评估。
J Crit Care. 2017 Feb;37:1-6. doi: 10.1016/j.jcrc.2016.07.020. Epub 2016 Aug 10.
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Effect of Extracorporeal Membrane Oxygenation Use on Sedative Requirements in Patients with Severe Acute Respiratory Distress Syndrome.
丙泊酚的聚乙二醇化减少了其对体外膜肺氧合（ECMO）组件的吸附。
Pharm Res. 2025 Jun 5. doi: 10.1007/s11095-025-03879-3.
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Pharmacokinetics of midazolam and hepatic cytochrome P450 3A activity in an in vivo extracorporeal membrane oxygenation rat model.咪达唑仑的药代动力学及体内体外膜肺氧合大鼠模型中肝脏细胞色素P450 3A活性研究
Sci Rep. 2025 Jun 3;15(1):19363. doi: 10.1038/s41598-025-03949-x.
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Pharmacokinetics of Dexmedetomidine in an In Vitro Circuit Model and In Vivo Extracorporeal Membrane Oxygenation Rat Model.右美托咪定在体外循环模型和体内体外膜肺氧合大鼠模型中的药代动力学
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