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用进废退!认知活动作为与阿尔茨海默病相关的认知衰退的保护因素。

Use it or lose it! Cognitive activity as a protec-tive factor for cognitive decline associated with Alzheimer's disease.

作者信息

Mistridis Panagiota, Mata Jutta, Neuner-Jehle Stefan, Annoni Jean-Marie, Biedermann Andreas, Bopp-Kistler Irene, Brand Dominique, Brioschi Guevara Andrea, Decrey-Wick Hedi, Démonet Jean-François, Hemmeter Ulrich, Kressig Reto W, Martin Brian, Rampa Luca, Savaskan Egemen, Stuck Andreas, Tschopp Philipp, Zekry Dina, Monsch Andreas

机构信息

Memory Clinic, University Centre for Medicine of Aging, Felix Platter Hospital, Basel, Switzerland.

Health Psychology, Department of Social Sciences, University of Mannheim, Germany.

出版信息

Swiss Med Wkly. 2017 Mar 1;147:w14407. doi: 10.4414/smw.2017.14407. eCollection 2017.

DOI:
10.4414/smw.2017.14407
PMID:28322422
Abstract

Because of the worldwide aging of populations, Alzheimer's disease and other dementias constitute a devastating experience for patients and families as well as a major social and economic burden for both healthcare systems and society. Multiple potentially modifiable cardiovascular and lifestyle risk factors have been associated with this disease. Thus, modifying these risk factors and identifying protective factors represent important strategies to prevent and delay disease onset and to decrease the social burden. Based on the cognitive reserve hypothesis, evidence from epidemiological studies shows that low education and cognitive inactivity constitute major risk factors for dementia. This indicates that a cognitively active lifestyle may protect against cognitive decline or delay the onset of dementia. We describe a newly developed preventive programme, based on this evidence, to stimulate and increase cognitive activity in older adults at risk for cognitive decline. This programme, called "BrainCoach", includes the technique of "motivational interviewing" to foster behaviour change. If the planned feasibility study is successful, we propose to add BrainCoach as a module to the already existing "Health Coaching" programme, a Swiss preventive programme to address multiple risk factors in primary care.

摘要

由于全球人口老龄化,阿尔茨海默病和其他痴呆症给患者及其家庭带来了毁灭性的影响,同时也给医疗系统和社会造成了重大的社会和经济负担。多种潜在可改变的心血管和生活方式风险因素与这种疾病有关。因此,改变这些风险因素并识别保护因素是预防和延缓疾病发作以及减轻社会负担的重要策略。基于认知储备假说,流行病学研究证据表明,低教育水平和认知不活跃是痴呆症的主要风险因素。这表明积极的认知生活方式可能预防认知衰退或延缓痴呆症的发作。基于这一证据,我们描述了一个新开发的预防项目,以刺激和增加有认知衰退风险的老年人的认知活动。这个项目名为“BrainCoach”,包括“动机性访谈”技术以促进行为改变。如果计划中的可行性研究成功,我们建议将BrainCoach作为一个模块添加到现有的“健康指导”项目中,这是一个瑞士的预防项目,旨在解决初级保健中的多种风险因素。

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