Shangkuan Wei-Chuan, Lin Hung-Che, Shih Cheng-Ping, Cheng Chun-An, Fan Hueng-Chuen, Chung Chi-Hsiang, Lin Fu-Huang, Tsao Chang-Huei, Chien Wu-Chien
National Defense Medical Center, Taipei, Taiwan.
Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Laryngoscope. 2017 Nov;127(11):2627-2635. doi: 10.1002/lary.26567. Epub 2017 Mar 21.
OBJECTIVES/HYPOTHESIS: We investigated incidences of hearing loss among patients with traumatic brain injury (TBI) to evaluate whether they had a higher risk of hearing loss than the general population.
Cohort study.
Inpatient data from the Taiwan National Health Insurance Research Database from January 1, 2000 to December 31, 2010 were recorded. Patients with TBI and a retrospective comparison cohort were analyzed. Each subject was individually traced from their index date to identify subjects who subsequently received a diagnosis of hearing loss. Cox regression analyses were applied to determine the risk of TBI-related hearing loss.
Follow-up data from the TBI and comparison cohorts were collected over 10 years for 553,286 and 1,106,572 patients, respectively. Multivariate analyses demonstrated that TBI significantly increased the risk of hearing loss (adjusted hazard ratio = 2.125, 95% confidence interval = 2.045-2.546, P = .027). In our subgroup analyses by type of injury, patients with TBI due to traffic injury had the highest associated risk of hearing loss compared with the risk of non-TBI traffic injury patients, followed by patients with crushing/cutting/piercing injuries and falls.
Our study shows that TBI led to a higher risk of long-term hearing loss. Traffic injuries were the most common injury related to hearing loss. Prevention, rather than treatment, may be the best policy for preventing hearing loss.
2b. Laryngoscope, 127:2627-2635, 2017.
目的/假设：我们调查了创伤性脑损伤（TBI）患者的听力损失发生率，以评估他们是否比普通人群有更高的听力损失风险。
队列研究。
记录了2000年1月1日至2010年12月31日台湾国民健康保险研究数据库中的住院患者数据。对TBI患者和回顾性对照队列进行了分析。从每个受试者的索引日期开始单独追踪，以确定随后被诊断为听力损失的受试者。应用Cox回归分析来确定TBI相关听力损失的风险。
TBI队列和对照队列的随访数据分别在10年内收集，涉及553,286名和1,106,572名患者。多变量分析表明，TBI显著增加了听力损失的风险（调整后的风险比=2.125，95%置信区间=2.045-2.546，P=.027）。在我们按损伤类型进行的亚组分析中，与非TBI交通伤患者相比，交通伤导致的TBI患者听力损失相关风险最高，其次是挤压/切割/刺伤和跌倒患者。
我们的研究表明，TBI导致长期听力损失的风险更高。交通伤是与听力损失相关的最常见损伤。预防而非治疗可能是预防听力损失的最佳策略。
2b。《喉镜》，127:2627-2635，2017年。
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