Liu Tingting
1 Emory University, Atlanta, GA, USA.
West J Nurs Res. 2018 Apr;40(4):537-561. doi: 10.1177/0193945916683184. Epub 2016 Dec 21.
Previous lifestyle intervention research targeting prediabetes has primarily focused on weight loss, blood glucose, and lipid abnormalities. Far less is known whether lifestyle interventions lower other biological and physical risk factors for cardiovascular disease in overweight/obese adults with or without prediabetes. The aim of the study was to determine if a health partner program reduced biological and physical cardiovascular risk factors in overweight/obese adults with and without prediabetes at 1 year. A secondary data analysis was performed using the Center for Health Discovery and Well Being database at Emory University in the United States. A total of 246 (30 prediabetics and 216 non-prediabetics) were included in the analysis. At the 1-year follow-up, compared with non-prediabetics, prediabetics had significant improvements in body mass index, fasting blood glucose, and insulin resistance. Prediabetics also had higher increases in cardiorespiratory fitness. However, the methodological limitations and predominately high socioeconomic status level prevent definitive conclusions and generalizations.
先前针对糖尿病前期的生活方式干预研究主要集中在体重减轻、血糖和血脂异常方面。对于生活方式干预是否能降低超重/肥胖的糖尿病前期或非糖尿病前期成年人患心血管疾病的其他生物和身体风险因素,人们所知甚少。该研究的目的是确定一项健康伙伴计划是否能在1年内降低超重/肥胖的糖尿病前期和非糖尿病前期成年人的生物和身体心血管风险因素。在美国埃默里大学健康发现与幸福中心数据库进行了二次数据分析。分析共纳入246人(30名糖尿病前期患者和216名非糖尿病前期患者)。在1年随访时,与非糖尿病前期患者相比,糖尿病前期患者在体重指数、空腹血糖和胰岛素抵抗方面有显著改善。糖尿病前期患者的心肺适能也有更高的提升。然而,方法学上的局限性以及主要为较高社会经济地位水平这一情况妨碍了得出明确结论和进行推广。