Gao Yunliang, Danforth Teresa, Ginsberg David A
Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, China; Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Department of Urology, SUNY Buffalo School of Medicine and Biomedical Sciences, Buffalo General Hospital, Buffalo, NY.
Urology. 2017 Jun;104:52-58. doi: 10.1016/j.urology.2017.03.006. Epub 2017 Mar 16.
To assess the management and types of urologic complications in spinal cord injury (SCI) patients and to explore the risk factors for these complications.
A total of 43 SCI patients with a median follow-up of 45 (range 40-50) years were included in this retrospective study. All medical charts were reviewed for demographics, urologic complications, and bladder management.
Recurrent urinary tract infection (UTI) was noted in all patients, with an average incidence of 6.1 cases per 5 years per person. UTI incidence peaked in the 1st and 10th 5-year intervals. Besides UTI, the most common complications were bladder stone (49%), hydronephrosis (47%), and vesicoureteral reflux (33%). Most complications initially occurred during the first 25 years post injury. Male gender, cervical injury, and condom catheter use were closely related to complications, particularly UTI and renal insufficiency. The bladder managements used for the longest period were condom catheter in men (79%) and clean intermittent catheterization in women (33%), with an average maintenance of 23.6 and 38.0 years, respectively.
With long follow-up, a wide and complex range of urologic complications occurred in SCI patients and continued to do so throughout the period of follow-up. A greater risk of urologic complications may be seen with certain factors (male gender, cervical SCI, and condom catheter use); however, all patients with SCI are at risk of urinary complications over time. Thus, even long-term patients who are thought to be "stable" require regular follow-up and surveillance.
评估脊髓损伤(SCI)患者泌尿系统并发症的处理情况及类型,并探讨这些并发症的危险因素。
本回顾性研究纳入了43例SCI患者,中位随访时间为45年(范围40 - 50年)。查阅所有病历,了解患者人口统计学资料、泌尿系统并发症及膀胱管理情况。
所有患者均出现复发性尿路感染(UTI),平均发病率为每人每5年6.1例。UTI发病率在第1个和第10个5年间隔期达到峰值。除UTI外,最常见的并发症为膀胱结石(49%)、肾积水(47%)和膀胱输尿管反流(33%)。大多数并发症最初发生在受伤后的前25年。男性、颈部损伤和使用阴茎套导尿管与并发症密切相关,尤其是UTI和肾功能不全。男性使用时间最长的膀胱管理方法是阴茎套导尿管(79%),女性是清洁间歇性导尿(33%),平均维持时间分别为23.6年和38.0年。
经过长期随访,SCI患者出现了广泛而复杂的泌尿系统并发症,且在整个随访期间持续存在。某些因素(男性、颈髓损伤和使用阴茎套导尿管)可能会增加泌尿系统并发症的风险;然而,所有SCI患者随着时间推移都有发生泌尿系统并发症的风险。因此,即使是被认为“稳定”的长期患者也需要定期随访和监测。