• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Quantifying the shifting landscape of B cell immunodominance.

作者信息

Dale Gordon A, Shartouny Jessica R, Jacob Joshy

机构信息

Department of Microbiology and Immunology and the Emory Vaccine Center, Emory University, Atlanta, Georgia, USA.

出版信息

Nat Immunol. 2017 Mar 22;18(4):367-368. doi: 10.1038/ni.3695.

DOI:10.1038/ni.3695
PMID:28323262
Abstract
摘要

相似文献

1
Quantifying the shifting landscape of B cell immunodominance.量化B细胞免疫显性的动态变化格局。
Nat Immunol. 2017 Mar 22;18(4):367-368. doi: 10.1038/ni.3695.
2
Comment on "Frequency of epitope-specific naive CD4+ T cells correlates with immunodominance in the human memory repertoire".关于“表位特异性初始CD4 + T细胞的频率与人类记忆库中的免疫显性相关”的评论
J Immunol. 2012 Jun 1;188(11):5205-6; author reply 5206. doi: 10.4049/jimmunol.1290018.
3
Modulation of DNA vaccine-elicited CD8+ T-lymphocyte epitope immunodominance hierarchies.DNA疫苗诱导的CD8+ T淋巴细胞表位免疫显性等级的调控
J Virol. 2006 Dec;80(24):11991-7. doi: 10.1128/JVI.01348-06. Epub 2006 Sep 27.
4
Crystal structures of murine MHC Class I H-2 D(b) and K(b) molecules in complex with CTL epitopes from influenza A virus: implications for TCR repertoire selection and immunodominance.与甲型流感病毒CTL表位复合的小鼠MHC I类H-2 D(b)和K(b)分子的晶体结构:对TCR库选择和免疫显性的影响
J Mol Biol. 2005 Feb 4;345(5):1099-110. doi: 10.1016/j.jmb.2004.11.023. Epub 2004 Dec 8.
5
CD8+ TCR Bias and Immunodominance in HIV-1 Infection.HIV-1感染中的CD8+TCR偏向性与免疫显性
J Immunol. 2015 Jun 1;194(11):5329-45. doi: 10.4049/jimmunol.1400854. Epub 2015 Apr 24.
6
Elimination of immunodominant epitopes from multispecific DNA-based vaccines allows induction of CD8 T cells that have a striking antiviral potential.从多特异性DNA疫苗中去除免疫显性表位可诱导具有显著抗病毒潜力的CD8 T细胞。
J Immunol. 2009 Jul 1;183(1):370-80. doi: 10.4049/jimmunol.0900505.
7
The immunodominant CD8 T cell response to the human cytomegalovirus tegument phosphoprotein pp65(495-503) epitope critically depends on CD4 T cell help in vaccinated HLA-A*0201 transgenic mice.人巨细胞病毒被膜磷蛋白 pp65(495-503)表位的免疫优势 CD8 T 细胞应答在接种 HLA-A*0201 转基因小鼠中严重依赖于 CD4 T 细胞的辅助作用。
J Immunol. 2011 Sep 1;187(5):2172-80. doi: 10.4049/jimmunol.1002512. Epub 2011 Aug 1.
8
Silencing an immunodominant epitope of hepatitis B surface antigen reveals an alternative repertoire of CD8 T cell epitopes of this viral antigen.沉默乙肝表面抗原的免疫优势表位揭示了该病毒抗原的 CD8 T 细胞表位的另一个替代库。
Vaccine. 2009 Dec 10;28(1):114-9. doi: 10.1016/j.vaccine.2009.09.096. Epub 2009 Oct 8.
9
T cell immunodominance and maintenance of memory regulated by unexpectedly cross-reactive pathogens.由意外交叉反应病原体调节的T细胞免疫显性和记忆维持。
Nat Immunol. 2002 Jul;3(7):627-34. doi: 10.1038/ni806. Epub 2002 Jun 3.
10
Of cats and men: immunodominance and the role of HLA-DP/DQ.猫与人类:免疫显性及HLA - DP/DQ的作用
Clin Exp Allergy. 2008 Nov;38(11):1709-11. doi: 10.1111/j.1365-2222.2008.03112.x.

引用本文的文献

1
BIDpred: unraveling B cell Immunodominance hierarchical pattern using statistical feature discovery and deep learning prediction.BIDpred:利用统计特征发现和深度学习预测揭示B细胞免疫优势层次模式。
Front Immunol. 2025 Aug 13;16:1646946. doi: 10.3389/fimmu.2025.1646946. eCollection 2025.
2
Peptide Platform as a Powerful Tool in the Fight against COVID-19.肽平台作为抗击新冠疫情的有力工具
Viruses. 2021 Aug 23;13(8):1667. doi: 10.3390/v13081667.
3
Antibody Responses Elicited by Immunization with BG505 Trimer Immune Complexes.

本文引用的文献

1
Defining B cell immunodominance to viruses.定义针对病毒的B细胞免疫显性。
Nat Immunol. 2017 Apr;18(4):456-463. doi: 10.1038/ni.3680. Epub 2017 Feb 13.
2
Implications of broadly neutralizing antibodies in the development of a universal influenza vaccine.广泛中和抗体在通用流感疫苗研发中的意义。
Curr Opin Virol. 2016 Apr;17:110-115. doi: 10.1016/j.coviro.2016.03.002. Epub 2016 Mar 28.
3
Complex Antigens Drive Permissive Clonal Selection in Germinal Centers.复杂抗原驱动生发中心的许可性克隆选择。
BG505 三聚体免疫复合物免疫诱导的抗体反应。
J Virol. 2019 Sep 30;93(20). doi: 10.1128/JVI.01188-19. Print 2019 Oct 15.
4
B Cell Competition for Restricted T Cell Help Suppresses Rare-Epitope Responses.B 细胞竞争获取受限的 T 细胞辅助抑制稀有表位反应。
Cell Rep. 2018 Oct 9;25(2):321-327.e3. doi: 10.1016/j.celrep.2018.09.029.
5
Corrigendum: Quantifying the shifting landscape of B cell immunodominance.勘误:量化B细胞免疫显性的变化态势。
Nat Immunol. 2017 May 18;18(6):705. doi: 10.1038/ni0617-705a.
Immunity. 2016 Mar 15;44(3):542-552. doi: 10.1016/j.immuni.2016.02.010. Epub 2016 Mar 3.
4
Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans.人类接种H5N1疫苗后对流感血凝素茎区产生广泛交叉反应性抗体应答
Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13133-8. doi: 10.1073/pnas.1414070111. Epub 2014 Aug 25.
5
Targeting the HA2 subunit of influenza A virus hemagglutinin via CD40L provides universal protection against diverse subtypes.通过CD40L靶向甲型流感病毒血凝素的HA2亚基可提供针对多种亚型的通用保护。
Mucosal Immunol. 2015 Jan;8(1):211-20. doi: 10.1038/mi.2014.59. Epub 2014 Jul 23.
6
High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination.高通量测序天然配对的抗体链为原始抗原决定簇决定流感疫苗接种后抗体反应提供了证据。
Clin Immunol. 2014 Mar;151(1):55-65. doi: 10.1016/j.clim.2013.12.008. Epub 2014 Jan 9.
7
Differences in antibody responses between trivalent inactivated influenza vaccine and live attenuated influenza vaccine correlate with the kinetics and magnitude of interferon signaling in children.三价灭活流感疫苗和减毒活流感疫苗引起的抗体反应差异与儿童干扰素信号转导的动力学和幅度相关。
J Infect Dis. 2014 Jul 15;210(2):224-33. doi: 10.1093/infdis/jiu079. Epub 2014 Feb 4.
8
Systems biology of vaccination for seasonal influenza in humans.人类季节性流感疫苗接种的系统生物学。
Nat Immunol. 2011 Jul 10;12(8):786-95. doi: 10.1038/ni.2067.
9
Original antigenic sin responses to influenza viruses.对流感病毒的原始抗原性错误反应。
J Immunol. 2009 Sep 1;183(5):3294-301. doi: 10.4049/jimmunol.0900398. Epub 2009 Jul 31.