Urlacher Elodie, Devaud Jean-Marc, Mercer Alison R
University of Otago, Department of Zoology, Dunedin, New Zealand.
Centre National de la Recherche Scientifique (CNRS), Centre de Recherches sur la Cognition Animale (UMR 5169), Toulouse, France.
PLoS One. 2017 Mar 21;12(3):e0174321. doi: 10.1371/journal.pone.0174321. eCollection 2017.
As honey bee populations worldwide are declining there is an urgent need for a deeper understanding of stress reactivity in these important insects. Our data indicate that stress responses in bees (Apis mellifera L.) may be mediated by neuropeptides identified, on the basis of sequence similarities, as allatostatins (ASTA, ASTC and ASTCC). Effects of allatostatin injection are compared with stress-related changes in learning performance induced by the honeybee alarm pheromone, isopentylacetate (IPA). We find that bees can exhibit two markedly different responses to IPA, with opposing effects on learning behaviour and memory generalisation, and that strikingly similar responses can be elicited by allatostatins, in particular ASTCC. These findings lend support to the hypothesis that allatostatins mediate stress reactivity in honey bees and suggest responses to stress in these insects are state dependent.
由于全球蜜蜂数量正在减少，迫切需要更深入地了解这些重要昆虫的应激反应。我们的数据表明，蜜蜂（意大利蜜蜂）的应激反应可能由基于序列相似性鉴定为咽侧体抑制素（ASTA、ASTC和ASTCC）的神经肽介导。将注射咽侧体抑制素的效果与蜜蜂报警信息素异戊酸乙酯（IPA）诱导的学习性能中与应激相关的变化进行比较。我们发现，蜜蜂对IPA可表现出两种明显不同的反应，对学习行为和记忆泛化有相反的影响，并且咽侧体抑制素，特别是ASTCC，可引发极其相似的反应。这些发现支持了咽侧体抑制素介导蜜蜂应激反应性的假说，并表明这些昆虫对应激的反应取决于状态。
