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在酒精使用不健康的患者中,感染艾滋病毒的患者比未感染艾滋病毒的患者接受循证酒精相关护理的可能性更低:一项退伍军人事务部全国性研究。

Among patients with unhealthy alcohol use, those with HIV are less likely than those without to receive evidence-based alcohol-related care: A national VA study.

作者信息

Williams Emily C, Lapham Gwen T, Shortreed Susan M, Rubinsky Anna D, Bobb Jennifer F, Bensley Kara M, Catz Sheryl L, Richards Julie E, Bradley Katharine A

机构信息

Health Services Research and Development (HSR and D) Veterans Affairs (VA) Puget Sound Health Care System, Center of Innovation for Veteran-Centered Value-Driven Care(COIN) Veterans Affairs (VA) Puget Sound Health Care System, Seattle, WA, United States; Department of Health Services, University of Washington, Seattle, WA, United States; Kaiser Permanente Washington Health Research Institute, Seattle, WA, United States.

Health Services Research and Development (HSR and D) Veterans Affairs (VA) Puget Sound Health Care System, Center of Innovation for Veteran-Centered Value-Driven Care(COIN) Veterans Affairs (VA) Puget Sound Health Care System, Seattle, WA, United States; Kaiser Permanente Washington Health Research Institute, Seattle, WA, United States.

出版信息

Drug Alcohol Depend. 2017 May 1;174:113-120. doi: 10.1016/j.drugalcdep.2017.01.018. Epub 2017 Mar 6.

Abstract

BACKGROUND

Alcohol use has important adverse effects on people living with HIV (PLWH). This study of patients with recognized unhealthy alcohol use estimated and compared rates of alcohol-related care received by PLWH and HIV- patients.

METHODS

Outpatients from the Veterans Health Administration who had one or more positive screen(s) for unhealthy alcohol use (AUDIT-C≥5) documented in their medical records 10/2009-5/2013 were eligible. Primary and secondary outcomes were brief intervention documented ≤14days after a positive alcohol screen, and a composite measure of any alcohol-related care (brief intervention, specialty addictions treatment or pharmacotherapy documented ≤365 days), respectively. Unadjusted and adjusted regression analyses compared alcohol-related care outcomes in PLWH and HIV- patients.

RESULTS

The sample included 830,825 outpatients (3,514 PLWH), reflecting 1,172,606 positive screens (1-5 per patient). For PLWH, 57.0% (95% confidence interval 55.4-58.5%) of positive screens were followed by brief intervention, compared to 73.8% (73.7-73.9%) for HIV- patients [relative rate: 0.77 (0.75-0.79), p<0.001]. After adjustment, comparable proportions were 61.0% (59.3-62.6%) for PLWH and 73.7% (73.6-73.8%) for HIV- patients [adjusted RR=0.83 (0.80-0.85); p<0.001]. Secondary outcome results were similar: for PLWH and HIV- patients, 67.1% (65.7-68.6%) and 77.7% (95% CI 77.7-77.8%) of positive screens, respectively, were followed by any alcohol-related care after adjustment [adjusted RR=0.86 (0.85-0.88), p<0.001].

CONCLUSIONS

In this large national sample of VA outpatients with unhealthy alcohol use, PLWH were less likely to receive alcohol-related care than HIV- patients. Special efforts may be needed to ensure alcohol-related care reaches PLWH.

摘要

背景

饮酒对艾滋病病毒感染者(PLWH)有重要的不良影响。本研究对已确认存在不健康饮酒行为的患者进行了评估,并比较了PLWH和未感染艾滋病病毒(HIV-)患者接受酒精相关护理的比例。

方法

2009年10月至2013年5月期间,退伍军人健康管理局的门诊患者若其病历中有一项或多项不健康饮酒筛查结果呈阳性(酒精使用障碍识别测试-消费版[AUDIT-C]≥5),则符合入选条件。主要和次要结局分别为酒精筛查阳性后14天内记录的简短干预,以及任何酒精相关护理的综合指标(简短干预、专业成瘾治疗或药物治疗记录在365天内)。未调整和调整后的回归分析比较了PLWH和HIV-患者的酒精相关护理结局。

结果

样本包括830,825名门诊患者(3,514名PLWH),共1,172,606次阳性筛查(每位患者1至5次)。对于PLWH,57.0%(95%置信区间55.4 - 58.5%)的阳性筛查后进行了简短干预,而HIV-患者为73.8%(73.7 - 73.9%)[相对率:0.77(0.75 - 0.79),p<0.001]。调整后,PLWH的可比比例为61.0%(59.3 - 62.6%),HIV-患者为73.7%(73.6 - 73.8%)[调整后相对风险率=0.83(0.80 - 0.85);p<0.001]。次要结局结果相似:调整后,PLWH和HIV-患者阳性筛查后接受任何酒精相关护理的比例分别为67.1%(65.7 - 68.6%)和77.7%(95%置信区间77.7 - 77.8%)[调整后相对风险率=0.86(0.85 - 0.88),p<0.001]。

结论

在这个全国性的大量存在不健康饮酒行为的退伍军人管理局门诊患者样本中,PLWH比HIV-患者接受酒精相关护理的可能性更小。可能需要做出特别努力,以确保PLWH能够获得酒精相关护理。

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