Abdel-Aziz Elzayat Mohamed, Barnett-Vanes Ashton, Dabour Mohamed Farag Elmorsy, Cheng Feng
Faculty of Medicine, Al-Azhar University Egypt, Cairo, Egypt.
Research Center for Public Health and Center for Global Health & Infectious Diseases, Tsinghua University, Beijing, China.
BMJ Open. 2017 Mar 21;7(3):e013198. doi: 10.1136/bmjopen-2016-013198.
The prevalence of asymptomatic bacteriuria (ASB) during pregnancy is poorly understood in Egypt-a country with a high birth rate.
To determine the prevalence of ASB among pregnant women booking at El Hussein and Sayed Galal Hospitals in Al-Azhar University in Egypt; and to observe the relationship between ASB prevalence and risk factors such as socioeconomic level and personal hygiene.
Obstetrics and gynaecology clinics of 2 university hospitals in the capital of Egypt. Both hospitals are teaching and referral hospitals receiving referrals from across over the country. They operate specialist antenatal clinics 6 days per week.
A cross-sectional study combining the use of questionnaires and laboratory analysis was conducted in 171 pregnant women with no signs or symptoms of urinary tract infection (1 case was excluded). Samples of clean catch midstream urine were collected and cultured using quantitative urine culture and antibiotic sensitivity tests were performed.
Of 171 pregnant women, 1 case was excluded; 17 cases (10%, 95% CI 5.93% to 15.53%) were positive for ASB. There was a statistically significant relation between the direction of washing genitals and sexual activity per week-and ASB. was the most commonly isolated bacteria followed by . Nitrofurantoin showed 100% sensitivity, while 88% of the isolates were resistant to cephalexin.
The prevalence of ASB seen in pregnant women in 2 tertiary hospitals in Egypt was 10%. and are the common organisms isolated. The direction of washing genitals and sexual activity significantly influences the risk of ASB. Pregnant women should be screened early for ASB during pregnancy; appropriate treatment should be given for positive cases according to antibiotic sensitivity screening. Cephalexin is likely to be of limited use in this management.
在埃及这个出生率很高的国家，人们对孕期无症状菌尿（ASB）的患病率了解甚少。
确定在埃及艾资哈尔大学的侯赛因医院和赛义德·加拉勒医院就诊的孕妇中ASB的患病率；并观察ASB患病率与社会经济水平和个人卫生等危险因素之间的关系。
埃及首都两家大学医院的妇产科诊所。两家医院均为教学和转诊医院，接收来自全国各地的转诊患者。它们每周运营6天专科产前诊所。
对171名无尿路感染体征或症状的孕妇进行了一项结合问卷调查和实验室分析的横断面研究（排除1例）。收集清洁中段尿样本并进行定量尿培养，同时进行抗生素敏感性测试。
171名孕妇中，排除1例；17例（10%，95%可信区间5.93%至15.53%）ASB呈阳性。生殖器清洗方向和每周性行为与ASB之间存在统计学显著关系。 是最常分离出的细菌，其次是 。呋喃妥因显示出100%的敏感性，而88%的分离株对头孢氨苄耐药。
埃及两家三级医院孕妇中ASB的患病率为10%。 和 是常见的分离菌。生殖器清洗方向和性行为显著影响ASB风险。孕妇在孕期应尽早进行ASB筛查；根据抗生素敏感性筛查结果，对阳性病例应给予适当治疗。头孢氨苄在这种治疗中可能用途有限。
