环状肉芽肿患者合并慢性肝炎伴肝肉芽肿：一例报告及文献复习
Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature.
作者信息
Alsahafi Majid, AlJasser Mohammed I, Kalia Sunil, Yang H M, Ramji Alnoor
机构信息
Division of Gastroenterology, University of British Columbia, Vancouver, BC, Canada; Department of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada.
出版信息
Case Rep Gastrointest Med. 2017;2017:8768529. doi: 10.1155/2017/8768529. Epub 2017 Feb 23.
Granuloma annulare (GA) is a benign granulomatous skin disorder of unknown etiology. GA is rarely associated with liver diseases. We report a unique case of chronic hepatitis with liver granulomas in a patient with GA. Despite an extensive workup, no clear etiology for the hepatitis was found. Based on the possible immune pathophysiology of GA and the presence of liver granulomas, the patient was treated with prednisone and azathioprine which resulted in complete normalization of the liver enzymes and concurrent improvement of GA. The association between liver diseases and GA is reviewed.
环状肉芽肿（GA）是一种病因不明的良性肉芽肿性皮肤病。GA很少与肝脏疾病相关。我们报告了1例GA患者合并慢性肝炎伴肝脏肉芽肿的独特病例。尽管进行了广泛检查，但未发现肝炎的确切病因。基于GA可能的免疫病理生理学及肝脏肉芽肿的存在，该患者接受泼尼松和硫唑嘌呤治疗，结果肝酶完全恢复正常，同时GA也有所改善。本文对肝脏疾病与GA之间的关联进行了综述。
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