Luedke Colten, Crawford William S, Payne Joshua, Sanchez Hugo B
Department of Orthopaedics, John Peter Smith Hospital, Fort Worth, TX, USA; Department of Orthopaedics, University of North Texas Health Science Center, Fort Worth, TX, USA.
Department of Orthopaedics, John Peter Smith Hospital, Fort Worth, TX, USA.
Arthroplast Today. 2015 Jun 23;1(2):31-35. doi: 10.1016/j.artd.2015.04.001. eCollection 2015 Jun.
We present a case of a 64-year old female with bilateral knee pain several months after undergoing staged bilateral TKA. Radiolucencies surrounding the keels of bilateral tibial components were found to represent metastatic poorly differentiated endometrial carcinoma. PET scan showed adrenal, pulmonary and tibial foci consistent with metastatic disease. No other cases of bilateral periprosthetic metastasis of endometrial carcinoma have been described in the literature. Metastases around orthopedic implants are a rare occurrence. The possibility of periprosthetic metastasis should remain in the differential diagnosis for any patient with a painful total joint arthroplasty, especially in the setting of a patient with a known diagnosis of cancer elsewhere in their body.
我们报告一例64岁女性，在接受分期双侧全膝关节置换术（TKA）数月后出现双侧膝关节疼痛。发现双侧胫骨假体龙骨周围的透亮区代表转移性低分化子宫内膜癌。正电子发射断层扫描（PET）显示肾上腺、肺部和胫骨病灶与转移性疾病相符。文献中未描述过其他双侧子宫内膜癌假体周围转移的病例。骨科植入物周围的转移很少见。对于任何接受全关节置换术且疼痛的患者，尤其是体内其他部位已确诊患有癌症的患者，假体周围转移的可能性应始终列入鉴别诊断范围。
