Martin John R, Spencer-Gardner Luke, Camp Christopher L, Stulak John M, Sierra Rafael J
Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, USA.
Arthroplast Today. 2015 Nov 21;1(4):99-102. doi: 10.1016/j.artd.2015.10.002. eCollection 2015 Dec.
This is one of the first documented cases of metal-on-metal (MoM) total hip arthroplasty cobalt cardiac toxicity that has led to patient death. A 69-year-old female presented to our institution with cardiac failure secondary to cobalt toxicity resulting from bilateral MoM total hip arthroplasty. Her presenting metal ion levels were a cobalt level of 199 ppb and a chromium level of 77 ppb. She underwent bilateral femoral revisions to remove the source of cobalt. On postoperative day 7, the patient sustained a cerebral infarct and eventually expired because of the insult. This case represents one of the first documented fatalities related to MoM cobalt cardiac toxicity.
这是有记录的首例金属对金属(MoM)全髋关节置换术导致钴中毒性心脏毒性并致使患者死亡的病例之一。一名69岁女性因双侧MoM全髋关节置换术引发钴中毒继发心力衰竭,前来我院就诊。她就诊时的金属离子水平为钴含量199 ppb,铬含量77 ppb。她接受了双侧股骨翻修手术以去除钴源。术后第7天,患者发生脑梗死,最终因该损伤而死亡。该病例是有记录的首例与MoM钴中毒性心脏毒性相关的死亡病例之一。