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在一名有复发性流产(RPL)病史的女性中,在西地那非和依诺肝素基础上加用脂肪乳后成功妊娠。

Successful pregnancy after Intralipid addition to sildenafil and enoxaparin in woman with history of recurrent pregnancy loss (RPL).

作者信息

Jerzak Malgorzata, Szafarowska Monika, Kniotek Monika, Gorski Andrzej

机构信息

Department of Gynecology and Oncological Gynecology, Military Institute of Medicine, Warsaw, Poland.

Department of Clinical Immunology, Transplantation Institute, University Medical School, Warsaw, Poland.

出版信息

Neuro Endocrinol Lett. 2016 Dec;37(7):473-477.

PMID:28326740
Abstract

OBJECTIVES

Does addition of Intralipid to sildenafil and enoxaparin immunotherapy improve pregnancy outcome?

MATERIALS AND METHOD

Report of a striking case of a patient with history of 4 recurrent pregnancy losses (RPL) and IVF failures.

RESULTS

Adding of Intralipid resulted in giving birth to a healthy male baby in the 3th IVF cycle.

CONCLUSION

Combination therapy that includes Intralipid may generate successful IVF outcome, although this problem merits further study, especially regarding safety issues.

摘要

目的

在西地那非和依诺肝素免疫治疗中添加脂肪乳剂是否能改善妊娠结局?

材料与方法

报告一例有4次复发性流产(RPL)病史且体外受精(IVF)失败的患者的显著病例。

结果

添加脂肪乳剂后,该患者在第3次IVF周期产下一名健康男婴。

结论

包括脂肪乳剂的联合治疗可能会产生成功的IVF结果,尽管这个问题值得进一步研究,特别是关于安全性问题。

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Neuro Endocrinol Lett. 2016 Dec;37(7):473-477.
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