Babu A, Verma R S
Division of Genetics, Beth Israel Medical Center, New York, New York.
Mol Gen Genet. 1988 Feb;211(2):367-8. doi: 10.1007/BF00330618.
The recent addition of restriction endonucleases in obtaining selective bands in the human genome has added a new dimension to molecular genetics. However, a considerable discrepancy exists in banding patterns produced by AluI in chromosomes 19 and 20, by MboI in chromosomes 4, 5, 8, 21 and 22 and by RsaI in chromosomes 12, 21 and 22. The principal causes of these differences are highlighted.
最近在人类基因组中获取选择性条带时添加的限制性内切酶为分子遗传学增添了新的维度。然而,AluI在19号和20号染色体上产生的条带模式、MboI在4号、5号、8号、21号和22号染色体上产生的条带模式以及RsaI在12号、21号和22号染色体上产生的条带模式存在相当大的差异。文中突出了这些差异的主要原因。