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一家参考中心梅毒的患病率及相关因素

Prevalence and factors associated with syphilis in a Reference Center.

作者信息

Gomes Natália Carolina Rodrigues Colombo, Meier Denise Andrade Pereira, Pieri Flávia Meneguetti, Alves Elaine, Albanese Silvia Paulino Ribeiro, Lentine Edvilson Cristiano, Arcêncio Ricardo Alexandre, Dessunti Elma Mathias

机构信息

Departamento de Enfermagem, Universidade Estadual de Londrina, Londrina, PR, Brasil.

Centro de Testagem e Aconselhamento, Londrina, PR, Brasil.

出版信息

Rev Soc Bras Med Trop. 2017 Jan-Feb;50(1):27-34. doi: 10.1590/0037-8682-0102-2016.

DOI:10.1590/0037-8682-0102-2016
PMID:28327799
Abstract

INTRODUCTION

: The implementation of the rapid test (RT) for syphilis increases access of vulnerable populations to early diagnosis and treatment, impacting the outcomes of infection. We aimed to assess the prevalence of and factors associated with syphilis in a Center for Testing and Counseling (CTC).

METHODS

: We conducted a cross-sectional study at a Reference Center for sexually transmitted disease (STD) and acquired immune deficiency syndrome in Londrina, Northern Paraná State, Southern Brazil. Data regarding the 5,509 individuals who underwent RT from June 2012 to December 2014 were collected from patient records and the CTC Information System and served as the basis to check associations of syphilis cases (346) and cases without syphilis (5,163). Nine patients' records were not found. OpenEpi was used to perform a prevalence analysis and determine odds ratios to assess the associations between sociodemographic and behavioral variables (independent variables) and cases of syphilis (dependent variable). An alpha value <0.05 was considered statistically significant.

RESULTS

: The prevalence of syphilis was 6.3%; higher in males (7.5%) than in females (4.3%, p <0.001). Syphilis was associated with an age of 25-34 years, little education, and single marital status. The main associated behavioral factors were men who have sex with men, drug users, STD patients, and those presenting with an STD in the last year. The use of alcohol, marijuana, cocaine, and crack was significantly associated with syphilis.

CONCLUSIONS

: Strategies for prevention and control of syphilis should be intensified, especially in populations identified as most vulnerable.

摘要

引言

梅毒快速检测(RT)的实施增加了弱势群体获得早期诊断和治疗的机会,影响感染结果。我们旨在评估检测与咨询中心(CTC)梅毒的患病率及相关因素。

方法

我们在巴西南部巴拉那州北部隆德里纳的性传播疾病(STD)和获得性免疫缺陷综合征参考中心进行了一项横断面研究。从患者记录和CTC信息系统中收集了2012年6月至2014年12月接受RT检测的5509名个体的数据,并以此为基础检查梅毒病例(346例)和非梅毒病例(5163例)之间的关联。未找到9名患者的记录。使用OpenEpi进行患病率分析并确定比值比,以评估社会人口学和行为变量(自变量)与梅毒病例(因变量)之间的关联。α值<0.05被认为具有统计学意义。

结果

梅毒患病率为6.3%;男性(7.5%)高于女性(4.3%,p<0.001)。梅毒与25-34岁、受教育程度低和单身婚姻状况有关。主要相关行为因素为男男性行为者、吸毒者、STD患者以及去年患有STD的人。饮酒、使用大麻、可卡因和强效纯可卡因与梅毒显著相关。

结论

应加强梅毒预防和控制策略,特别是在被确定为最脆弱的人群中。

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