Graduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Laboratory of Technological Innovation in Health, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
PLoS One. 2024 Sep 6;19(9):e0296481. doi: 10.1371/journal.pone.0296481. eCollection 2024.
The infection caused by Treponema pallidum remains a severe public health problem, with a high prevalence in individuals over 60 years. However, research into infections such as syphilis continues to be neglected in geriatrics. This study aims to evaluate data on the detection rate of syphilis in Brazil, in individuals between 60 and 120 years, by characterizing the epidemiological profile and respective factors associated with it, in addition to performing a temporal trend analysis, from 2010 to 2020.
Ecological, time-series study, which started with the collection of notifications from the database of the Information System on Compulsory Notification of Diseases. The epidemiological profile was characterized based on sociodemographic variables. The Statistical Package for the Social Sciences program, version 19.0, was used for incidence and prevalence analysis. The 2010 census by the Brazilian Institute of Geography and Statistics and projections for older people were considered. In the trend analysis, the Joinpoint regression model was used.
There was an upward variation in the detection of syphilis in older people from 2010 to 2018, with a peak in 2018. In 2019, there was a slight reduction in the notification of cases, which was accentuated in 2020. The prevalence of the infection was equivalent to 12.84 cases for each 100,000 Brazilians, with a mean age of 68.04 years (±7.15) for those between 60 and 120 years, being higher in white and black males. The highest proportion of older people with syphilis occurred in the South and Southeast regions. However, the trend analysis showed a significant and homogeneous increase in all regions of Brazil, for both sexes and all age groups.
There is a tendency for an increase in cases of syphilis in older people, which reinforces the need to plan health actions to combat the disease in this population.
苍白密螺旋体引起的感染仍是一个严重的公共卫生问题,60 岁以上人群的感染率较高。然而,老年医学领域对梅毒等感染的研究仍被忽视。本研究旨在评估 2010 年至 2020 年期间巴西 60 至 120 岁人群梅毒检测率的数据,通过描述流行病学特征及其相关因素,对其进行评估,并进行时间趋势分析。
这是一项生态、时间序列研究,首先从法定传染病报告信息系统数据库中收集报告。根据社会人口学变量对流行病学特征进行描述。采用社会科学统计软件包(SPSS)版本 19.0 进行发病率和患病率分析。考虑了 2010 年巴西地理与统计研究所的人口普查数据和对老年人的预测数据。在趋势分析中,使用 Joinpoint 回归模型。
2010 年至 2018 年,老年人梅毒检测呈上升趋势,2018 年达到峰值。2019 年,梅毒病例报告略有减少,2020 年则更为明显。感染的流行率相当于每 10 万巴西人中 12.84 例,60 至 120 岁人群的平均年龄为 68.04 岁(±7.15),白人男性和黑人男性的发病率较高。南部和东南部地区的老年梅毒患者比例最高。然而,趋势分析显示,巴西所有地区、所有性别和所有年龄组的梅毒病例都呈显著且均匀的上升趋势。
老年人群中梅毒病例呈上升趋势,这表明需要制定卫生行动来应对该人群的疾病。