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羟基磷灰石面部软组织填充的前瞻性三维分析

Prospective 3D analysis of facial soft tissue augmentation with calcium hydroxylapatite.

作者信息

Simunovic Filip, Schlager Stefan, Montanari Michaela, Iblher Niklas

机构信息

a Department of Plastic and Hand Surgery , Freiburg University Medical Center , Freiburg , Germany.

b Department of Biological Anthropology , University of Freiburg , Freiburg , Germany.

出版信息

J Cosmet Laser Ther. 2017 Oct;19(5):283-289. doi: 10.1080/14764172.2017.1307411. Epub 2017 Mar 22.

Abstract

BACKGROUND

Facial rejuvenation is an expanding field with an increasing number of treatment modalities. Several non-autologous filler materials are available for soft tissue augmentation. Calcium hydroxylapatite (CaOH) is aimed at increasing collagen neosynthesis and thereby producing long-term augmentation effects. Despite a multitude of observational reports, the field is suffering from lack of quantitative morphometric evaluation methods.

OBJECTIVE

The objective of this proof-of-principle study was to investigate whether the effects of facial tissue augmentation with CaOH (RADIESSE™) can be quantified and followed up using 3D surface scanning.

METHODS

3 female subjects received augmentation of the mid and lower face with CaOH. The faces were recorded prior, directly after, and two weeks and six months after the injection using standardized photos and 3D scanning. Computational analysis allowed quantifying the change in volume and displacement of the facial surface. Additionally, a patient satisfaction questionnaire was administered.

RESULTS

In all subjects, increase in facial volume could be quantified and was present after two weeks and six months.

CONCLUSIONS

3D surface scanning is an adequate tool for objective quantification of changes after facial augmentation with filler materials. Persistent volume augmentation after CaOH injections could be quantified after two weeks and six months. Evidence level: IV.

摘要

背景

面部年轻化是一个不断发展的领域,治疗方式越来越多。有几种非自体填充材料可用于软组织填充。羟基磷灰石(CaOH)旨在增加胶原蛋白的新合成,从而产生长期的填充效果。尽管有大量的观察报告,但该领域缺乏定量形态学评估方法。

目的

本原理验证研究的目的是调查使用3D表面扫描能否对用CaOH(瑞蓝™)进行面部组织填充的效果进行量化和随访。

方法

3名女性受试者接受了用CaOH对中下面部的填充。在注射前、注射后即刻、注射后两周和六个月使用标准化照片和3D扫描对面部进行记录。通过计算分析可以对面部表面的体积变化和位移进行量化。此外,还进行了患者满意度问卷调查。

结果

在所有受试者中,面部体积的增加都可以被量化,并且在两周和六个月后都存在。

结论

3D表面扫描是一种用于客观量化填充材料面部填充后变化的合适工具。CaOH注射后持续的体积增加在两周和六个月后都可以被量化。证据水平:IV。

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