Friedman Shelly, Schnoor Patricia
*Scottsdale Institute For Cosmetic Dermatology, Scottsdale, Arizona; †Capillus, Miami, Florida.
Dermatol Surg. 2017 Jun;43(6):856-867. doi: 10.1097/DSS.0000000000001114.
Photobiomodulation, also referred to as low-level laser therapy (LLLT), has been studied and used for (among other diseases) the promotion of hair regrowth.
OBJECTIVE/MATERIALS AND METHODS/RESULTS: A clinical study was developed to define the physiologic effects that occur when the human hair follicle and surrounding tissue structures are exposed to laser light using a novel device that is fitted with an array of laser diode sources operating at 650 nm and placed inside a sports cap to promote discretion while in use. The study demonstrates that low-level laser treatment of the scalp every other day for 17 weeks using the HANDI-DOME LASER device is a safe and effective treatment for androgenetic alopecia in healthy females between the ages of 18 to 60 with Fitzpatrick skin Types I to IV and Ludwig-Savin Baldness Scale I-2 to II-2 baldness patterns. Subjects receiving LLLT at 650 nm achieved a 51% increase in hair counts as compared with sham-treated control patients in this multicenter randomized controlled trial.
These results suggest that the emerging technology of low-level laser therapy may play a potentially significant role in health care providers' armamentarium for the disease androgenic alopecia.
光生物调节，也称为低强度激光疗法（LLLT），已被研究并用于（以及其他疾病）促进头发生长。
目的/材料与方法/结果：开展了一项临床研究，以确定当使用一种新型设备将人毛囊及周围组织结构暴露于激光时所产生的生理效应。该设备配备了一系列工作在650纳米的激光二极管光源，并放置在运动帽内，以便在使用时保持隐秘性。研究表明，对于年龄在18至60岁、 Fitzpatrick皮肤分型为I至IV型且Ludwig-Savin秃发量表为I-2至II-2秃发模式的健康女性雄激素性脱发患者，每隔一天使用HANDI-DOME激光设备对头皮进行低强度激光治疗17周是一种安全有效的治疗方法。在这项多中心随机对照试验中，接受650纳米低强度激光治疗的受试者与假治疗对照患者相比，毛发数量增加了51%。
这些结果表明，低强度激光疗法这一新兴技术可能在医疗保健提供者治疗雄激素性脱发的手段中发挥潜在的重要作用。
