Department of Dermatology, State University of New York, SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY, 11203, USA.
Dermatology Service, VA New York Harbor Healthcare System Brooklyn Campus, Brooklyn, NY, USA.
Arch Dermatol Res. 2022 Apr;314(3):239-246. doi: 10.1007/s00403-021-02231-0. Epub 2021 May 3.
There is increasing demand for home-based devices for the treatment of dermatologic conditions and cosmesis. Commercially available devices include intense pulsed light, laser diodes, radiofrequency, light-emitting diodes, and ultraviolet B phototherapy. The objective of this report is to evaluate the current evidence regarding the efficacy and safety of home-based devices for the treatment of skin conditions. A systematic search of PubMed, Embase, and Cinahl was conducted on November 9, 2020 using PRISMA guidelines. Original research articles that investigated the efficacy and safety of home-based devices for dermatologic use were included. Bibliographies were screened for additional relevant articles. Strength of evidence was graded using the Oxford Centre for Evidence-Based Medicine guidelines. Clinical recommendations were then made based on the quality of the existing literature. After review, 37 clinical trials were included-19 were randomized controlled trials, 16 were case series, and 2 were non-randomized controlled trials. Ultimately, from our analysis, we recommend the home-based use of intense pulsed light for hair removal, laser diodes for androgenic alopecia, low power radiofrequency for rhytides and wrinkles, and light-emitting diodes for acne vulgaris. Trials investigating ultraviolet B phototherapy for psoriasis revealed mixed evidence for home treatments compared to clinic treatments. All devices had favorable safety profiles with few significant adverse events. Limitations to our review include a limited number of randomized controlled trials as well as a lack of data on the long-term efficacy and safety of each device.
人们对皮肤科疾病和美容治疗的家用设备的需求日益增长。市售设备包括强脉冲光、激光二极管、射频、发光二极管和中波紫外线光疗。本报告的目的是评估家用设备治疗皮肤疾病的疗效和安全性的现有证据。根据 PRISMA 指南，于 2020 年 11 月 9 日在 PubMed、Embase 和 Cinahl 上进行了系统搜索。纳入了研究家用设备皮肤科应用的疗效和安全性的原始研究文章。对参考文献进行了筛选，以寻找其他相关文章。根据牛津循证医学中心的证据分级标准对证据强度进行了分级。然后根据现有文献的质量提出了临床建议。经过审查，共纳入 37 项临床试验，其中 19 项为随机对照试验，16 项为病例系列研究，2 项为非随机对照试验。最终，根据我们的分析，我们建议在家中使用强脉冲光进行脱毛，使用激光二极管治疗雄激素性脱发，使用低功率射频治疗皱纹和皱纹，使用发光二极管治疗寻常痤疮。针对中波紫外线光疗治疗银屑病的试验显示，与诊所治疗相比，家庭治疗的证据混杂。所有设备均具有良好的安全性，仅有少数严重不良事件。我们的综述存在一些局限性，包括随机对照试验数量有限，以及缺乏每种设备长期疗效和安全性的数据。
