Bebb Owen, Hall Marlous, Fox Keith A A, Dondo Tatendashe B, Timmis Adam, Bueno Hector, Schiele François, Gale Chris P
Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
York Teaching Hospital NHS Foundation Trust, York, UK.
Eur Heart J. 2017 Apr 1;38(13):974-982. doi: 10.1093/eurheartj/ehx008.
To investigate the application of the European Society of Cardiology Acute Cardiovascular Care Association quality indicators (QI) for acute myocardial infarction for the study of hospital performance and 30-day mortality.
National cohort study (n = 118,075 patients, n = 211 hospitals, MINAP registry), 2012-13. Overall, 16 of the 20 QIs could be calculated. Eleven QIs had a significant inverse association with GRACE risk adjusted 30-day mortality (all P < 0.005). The association with the greatest magnitude was high attainment of the composite opportunity-based QI (80-100%) vs. zero attainment (odds ratio 0.04, 95% confidence interval 0.04-0.05, P < 0.001), increasing attainment from low (0.42, 0.37- 0.49, P < 0.001) to intermediate (0.15, 0.13-0.16, P < 0.001) was significantly associated with a reduced risk of 30-day mortality. A 1% increase in attainment of this QI was associated with a 3% reduction in 30-day mortality (0.97, 0.97-0.97, P < 0.001). The QI with the widest hospital variation was 'fondaparinux received among NSTEMI' (interquartile range 84.7%) and least variation 'centre organisation' (0.0%), with seven QIs depicting minimal variation (<11%). GRACE risk score adjusted 30-day mortality varied by hospital (median 6.7%, interquartile range 5.4-7.9%).
Eleven QIs were significantly inversely associated with 30-day mortality. Increasing patient attainment of the composite quality indicator was the most powerful predictor; a 1% increase in attainment represented a 3% decrease in 30-day standardised mortality. The ESC QIs for acute myocardial infarction are applicable in a large health system and have the potential to improve care and reduce unwarranted variation in death from acute myocardial infarction.
探讨欧洲心脏病学会急性心血管护理协会急性心肌梗死质量指标(QI)在医院绩效和30天死亡率研究中的应用。
2012 - 2013年全国队列研究(n = 118,075例患者,n = 211家医院,MINAP注册登记)。总体而言,20个质量指标中的16个可以计算。11个质量指标与GRACE风险调整后的30天死亡率呈显著负相关(所有P < 0.005)。关联程度最大的是基于机会的综合质量指标高达成率(80 - 100%)与零达成率相比(优势比0.04,95%置信区间0.04 - 0.05,P < 0.001),达成率从低水平(0.42,0.37 - 0.49,P < 0.001)增加到中等水平(0.15,0.13 - 0.16,P < 0.001)与30天死亡率风险降低显著相关。该质量指标达成率每增加1%与30天死亡率降低3%相关(0.97,0.97 - 0.97,P < 0.001)。医院差异最大的质量指标是“非ST段抬高型心肌梗死患者接受磺达肝癸钠治疗”(四分位间距84.7%),差异最小的是“中心组织”(0.0%),7个质量指标显示差异极小(<11%)。GRACE风险评分调整后的30天死亡率因医院而异(中位数6.7%,四分位间距5.4 - 7.9%)。
11个质量指标与30天死亡率显著负相关。患者对综合质量指标达成率的提高是最有力的预测因素;达成率每增加1%代表30天标准化死亡率降低3%。欧洲心脏病学会急性心肌梗死质量指标适用于大型医疗系统,有可能改善护理并减少急性心肌梗死死亡中不必要的差异。